Bryan Johnson stops rapamycin

That’s precisely why he’s filthy rich :slight_smile:

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Agree with your statement, but he didn’t have to make a product. He could have just explained his routine.

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Do you know how much profit he makes from Blueprint products?

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Well, why didn’t Elon Musk stop when he made his first $10B, 50B or even $100B. And why doesn’t he stop now, well it seems he wants to be the first trillionaire and also wants to keep doing what he enjoys doing, and what excites him. By same talking BJ does it because he enjoys doing it, and it gives him purpose, plus why not make money with it also. I think I had listed to him in one of his podcasts a year or so ago, and the impression I got was that he was hopping his protocol/products will be so revolutionary to health and longevity that every person in the world would end up using/buying his products, hence I think somewhere in one his dream he envisioned himself giving interviews while being the richest man in the world while also being some sort of the savior of humanity, or maybe the savior of health of humanity LOL. The more I listened to him the more I got that impression.

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It could be a messianic feeling.

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I agree that most successful entrepreneurs don’t stop once they’ve hit a financial target.

I am a fan of his because his goal of making people healthier is admirable. I also have no problem with him cashing in on that endeavor. (For example, I don’t know much about Brad Standfield, other than he seems knowledgeable and very legit, so I think more power to him for selling a supplement). If one day Kaeberlein cashes in, I’ll be thrilled for him, too.

But, this assumes that everything he is selling is truly high quality and he remains honest. I am taking his Essential Capsule and happy it exists so I can reduce the number of pills I’m taking and not worry that what the label says is accurate.

I’m not thrilled to learn from the video how he overpriced the whole body mri package, but I’m much less happy to hear about his seemingly insincere reasons for stopping Rapa (charging too much for something good is different than not being honest, to me). I like him because I trust him, and once that goes, and it might now be going, it does dampen my enthusiasm and definitely hurts my blind willingness to try anything he is selling.

On another note, I was reading in another thread about increased heart rates relating to a different topic, so I looked at my Oura resting heart rate chart last night and see mine has started going up since April, which is when I started taking rapa. Might be unrelated and I have zero idea at what point an increase is not ok. Just sharing…

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I’ll let you in on a secret.

image

Go to optispan.life.

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RHR is a complex biomarker. Although I like mine to be below 50 ideally I am not stressed when it is higher. Normally getting drunk increases it and it takes two days at least for it to drop back down.

I find Alpha Keto Glutarate supplementation increases it as well.

I haven’t notice rapamycin pushing it up, but again that is not necessarily bad all else being equal if your cardiac mitochondria are more efficient you would expect a higher heart rate.

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OH F!!! Mine is WAAAAY higher than 50…

I’m now off to google what is normal for a woman my age.

I feel so great on rapa, it would take a LOT for me to give it up. Out of my cold dead hands, as they say.

And thanks for that comment because hearing that a more efficient cardiac mitochondria could do that makes me feel much better!!! :). I don’t really understand much about any of the inner workings and I really should never be posting on here :slight_smile:

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Ah that “trust” word that everybody is obsessed with and in my books does even exist. You can NOT and should NOT trust anyone EVER (with important things in your life that is, such as health as an example, but you could trust someone if they told you they sow a gallon of milk on sale though lol).
So, no I don’t trust any of them nor do I assume they are even saying the truth unless of course what they say can be verified (by outside/third party sources) and also happens to be in the category that makes sense to me. You can never ignore the gut feeling (believe it or not) nor should you ignore the saying “if it’s too good to be true, it is not true”.
The rest of it I agree, I can’t blame anyone out there in the longevity field trying to make money of of it.

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How did I not know about this… and brilliant!!! If I lived in Seattle, I’d be curious about the program and cost.

I am not addicted, but it has a material short term effect on the metabolism. Hence I record what I drink so I can adjust for it.

There is an interesting question as to whether the negative effects of particularly acetaldehyde can be adjusted for.

Incidentally I have not had any alcohol now for two days, but intend drinking tomorrow and probably Monday.

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the problem in this domain is lack of consequences and skin in the game. when it comes to people’s health, there’s a reason why it’s extremely difficult and laborious to innovate in the medical space: you might kill people. and thus the liability that comes with it.

in the health industry where people’s personas and their ‘word’ is what they’re selling, there is a lack of equivalent accountability when they end up shown to be wrong, or worse, grifters. sure, these entrepreneurs can just lose money and followers, but again, comparing consumer products to health advice and health products is not a one to one equivalence.

the most morally reprehensible are those who make claims, and default to either ‘this is not health advice’ or ‘i’m just reporting the science, things can change.’ i don’t mind objections to this since i’m aware this is a relatively contrarian position, but i believe all these supposed experts who are just ‘providing information’ are doing quite the opposite, and they know that. and they know nothing will happen to them if it turns out they’re wrong, because they’ve simply provided these disclaimers. they know (or perhaps don’t, which makes me question their intelligence) that ultimately people follow them because they want someone to take advice from with regards to their health. you really think these experts are naive enough to imagine that everyone who follows them is just ‘listening objectively and then doing their complete own independent research and thinking to arrive at their own conclusions on how to manage their health’?

nothing irritates me more than these people. i believe in the ancient conception of skin in the game, and that means that your reputation should be ruined (if not your life) in accordance with the consequences of your actions, which in the health space is: leading people on and possibly having made their health/life worse, and let’s not even go down to ‘killing people’. defaulting to ‘everyone is an adult and has to take responsibility for their own actions’ is a cop out precisely because these people are doing everything in their capability to influence your thinking. sometimes they’re even blatant about it, but again, know there are little consequences.

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I don’t think Bryan ever expected to become so famous. Even “regular” people have heard of him at this point. He’s doing videos with celebrities (like Steve Aoki) who have nothing to do with anti aging. He even appeared on Piers Morgan’s show.

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It’s all organic and nothing fake as well which makes it even better. Feels like he/they are winging it and succeeding.

People seem positive

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Strange, because for most of these health influencers, I don’t think they are trying to get people to follow their health advice. Most simply want the clicks, engagement and commercial success. They’ll say whatever it is they think will bring them money, whether it has a good, bad, or indifferent effect on your health means exactly zero to them. As the saying goes “it’s nothing personal, it’s just business.”

Now, there are true believers among them, who really believe in what they’re saying/selling, but I think they’re a small minority. Most are garden variety grifters, whose grift happens to be the wellness field, but it could have just as well been politics, business, religion or anything where the absence of morals and outsized avarice leads them to do their dance.

FWIW, my gut feeling - obviously I have no proof one way or another - is that BJ is a true believer. That is not incompatible with a bit of commerce, if there’s an opportunity to make some extra dough, he’ll gladly take it, that’s the business guy in him, but that doesn’t mean he doesn’t believe in what he says. I might be wrong of course, but that’s my sense of him… but then again, I haven’t looked much into him or his whole shtick.

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It is true, what the market wants, they supply. In a sense they are doing well using the system as it was intended. I personally wouldn’t sell very dangerous drugs, or the next super palatable high sodium food, like instant noodles to third world countries, but some people do that. Nor would I create a casino only for high spenders relative to income, or other similar things that provide what people demand and which I benefit from. Neither would I provide people a source of information when they want to quit their very safe medication their doctor prescribed to them in a way that keeps their attention on what I say, and makes them click on advertisements or buy a supplement, course, or book I have an affiliation with.

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his concierge program is $25K/year

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So Optispan is $25 K/year.
Peter Attia practice rumored to be $100 K/year or higher. $2500 one time for Early Medical.
Bryan Johnson’s current Blueprint is $4 K/year without the MRI scans + CAC.

I’m not saying which is better, just stating the apparent facts, and that they are in some technical definition competitors.

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@AnUser, Attia was 150k a year as of a couple years ago. One person said such a rip off and they did not reenroll, fwiw. Another person told me he heard about it from some others who are patients and everyone agrees it’s a rip, but they are so rich they just do it. Attia can, so bless him. Blueprint at least covers food and supplements! :). I personally can’t justify the cost of his food because I come close to making some of that myself anyway (nutty pudding etc), but it seems appealing. And some of his other stuff is just too high in sat fat for me. I do question why he added that in his protein powder?

Attia also has some full body MRI and other testing available in Palo Alto. I looked into the pricing a year or two ago, back when I trusted everything that came out of his mouth, and it was, if I recall (my memory doesn’t mean much), perhaps closer to 6-8k? I just know it was enough I didn’t consider it. A lot of it was repetitive for me, like a CAC etc.

@sandesh808 do you happen to know what optispan includes. That is a lot, so I would think it has to include all medical care, as an Attia for 150 would?

EDIT: I searched my inbox and found attia’s thing. I was way off… black membership was 14k and core membership was 7k
Here is what it included

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