I guess his kid’s blood isn’t good enough either… cast off like his rapamycin dosing. I am sure his kid - Talmadge (the name means pouch - wallet, begger’s bag), is pleased to be out of his dad’s youth intervention.
Immortality-Obsessed Tech Guy Trying New Technique That Involves Removing “All Blood From Body”
Given my experience with Plasma Exchange (6 treatments over 3 months, with minimal or non-noticeable improvements) I think he’s wasting his time and money with this new focus on TPE. He’s in good shape, I doubt he will see any benefit. Sometimes I suspect he does things just because they are unusual, expensive and generate good amount press or attention (even if they don’t provide any value).
His team of doctors are probably all yes men optimizing for appeasing Bryan and making the money spent consulting him or whatever worthwhile for him. People are chimps, unless there is a rock solid system in place to prevent this, it will happen. That might be why he put a bunch of weird elixirs in his hair serum that he later removed after one YouTuber commented on it, seemingly.
“… looking as uncannily youthful as ever.” Quote from the article - really?!? Hahaha!
I am with the anorexic assessment.
Doesn’t look a day over 15.
His post on X notes that the anti aging effects were not seen at the end of the study, only the middle, confirming my assessment here.
It’s curious that despite this, he still proceeds with TPE + IVIG. Some thoughts:
I think he’s becoming a media hound instead of actually trying to live longer nowadays. Whatever keeps him in the headlines…
And now this on NPR. I think Matt Kaeberlein was too kind to Bryan… lol
Bryan’s reasons for stopping rapamycin after 5 years… infections and heart rate… could have been too much rapamycin too often. It’s the dose - dummy.
Link: Tech entrepreneur Bryan Johnson discusses his quest to slow aging : NPR
MATT KAEBERLEIN: I think there’s value in these individual N-of-1 experiments where people are testing different things on themselves, but it’s never going to be accepted by the broader medical community or regulatory agencies. We need the more rigorous clinical trials.
MARTÍNEZ: And Johnson himself has admitted that some things he’s tried have not worked. Take rapamycin, for example. The drug has been shown to slow down the aging process in mice, but it is unproven in humans. Johnson took it for five years before stopping. He posted on X that he decided to stop taking the drug because of side effects such as infections and an increased heart rate.
Sadly if Bryan really did dose rapamycin for 5 years… he probably already gained a huge life extension benefit. But, will credit everything but rapamycin.
Not wanting to be conspiratorial… but Bryan could be paid off… in more ways than cash… by big pharma to poo-poo rapamycin. It’s benefits can hurt the bottom line in profits.
As Matt Kaeberlein said in one of his podcast… do you trust him… do you know his motivation?
He is obviously self promoting to the point of satire… and mockery. No such thing as bad press. Lol.
I don’t think you need to consider conspiracies… Just him taking rapamycin and doing “well” can easily be ascribed to rapamycin and not all the things he’s selling and taking, so I can see an incentive for him to dump rapamycin.
But ultimately it doesn’t matter. Everyone should make the best decisions for him or herself based on good data.
Exactly.
Works for me… I am definitely getting benefits well past my shelf-life.
Going for top shelf instead. Hahaha!
Hmmm… wasnt he charging twice as much for an expensive body scan?
Bryan talks about over priced supplements. Maybe take the basics D… K2 , Omega 3,
Taurine, Creatine, B12… melatonin and rapamycin…and call it good. 
no, that was two scans plus advanced AI analysis
The idea that COG should determine the retail price is absurd.
And now this…
Byran… you can then say, now we have a situation where the heart is 37, can we get the heart to be 36 or 35?
Got you there buddy…
According to two Coronary Calcium Scans… at almost 67 years… my heart is that of someone less than the age of 35.
I think my ears are younger than his too… lol.
Finasteride or something made you heart disease free, this should last until chronological age 90+ or something.
Did you do any scans to look at soft plaque so there’s nothing dangerous there?
Yes, I have taken a daily dose of finasteride since about 33 years old… we are just seeing its benefits in reduced prostate… keeping one’s hair… and in latest studies… it manages cholesterol in the blood. Win…win… win.
Just had my finasteride… tadalafil and minoxidil - my before bed medications.
I want to do a Cleery for soft plaque… right now takes multiple visits to a center… then a doctor… and the cost… not making it really practical. Maybe in a few years.
VO2max of 64.29 is pretty insane, especially at his age. He must be doing something right, at least his consistent exercise.
For what reason did he target increasing it further? Or was this a byproduct of another optimal exercise protocol, for example?
What does this mean from his post?
5x higher survival rate being in the top 2.5% of VO2 max in your age bracket
Yeah, not to pile on but what if everyone in his age bracket finds out about this and they all improve by 24%? Does he need to try harder and still be in the top 2.5% of that new group in order to get the benefit? Doesn’t make sense.
