Bradycardia and low resting heart rates

I might finally be figuring out what you’re doing with the Citrate. SCFA are HDAC inhibitors. They eat organic acids or indigestible fiber or polysaccharides. Citrate is an organic acid. So it could be a good food for the good guys.

Does it cause any gas at this level? 2 grams 3 times a day? Do you know which SCFA it makes more of? You’ve got me thinking about it. Thanks,

I’ve seen various studies on resting HR and mortality. Lower is good.

Mine is definitely higher than I want it to be. Not uncommonly its between 70 and 80 in the morning, and it’s rarely under 60. Not sure what I can do about it. What they tell you to do is exercise, and I get a lot of exercise.

1880e53.pdf (nih.gov)

“Results from this meta-analysis suggest the risk f all-cause and cardiovascular mortality increased by 9% and 8% for every 10 beats/min increment of resting heart rate. Compared with 45 beats/min, the risk of all-cause mortality increased significantly with increasing resting heart rate in a linear relation, but a significantly increased risk of cardiovascular mortality was observed at 90 beats/min.”

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No gas is created even at 40g per day divided into 8 doses of 5g. It is absorbed slowly into cells and converted by ACLY into acetyl-CoA that feeds into cellular metabolisn and is in part used by the RNA pol II complex to acetylate the histone. Unmetabolised citrate can also inhibit glycolysis. This can happen at high doses.

@Dexter_Scott Here’s an interview I did with Dr Ben Levine on this “strong heart” question. It might help.

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This July, mine dropped from its usual 55bpm down to 42bpm, with a brief waking low of 37bpm, for reasons I never got to the bottom of. According my Fitbit, the drop took five days, then the recovery to 55bpm took about three weeks. During the 42-47 bpm part, I just felt wrong. I didn’t like it one bit. I was minded to get an ECG but never got around to it. My consumer devices didn’t detect any A Fib and my exercise performance seemed unaffected, but the feeling was disturbing.

My unsupported extrapolation from this n=1 is that there’s an optimum HR for each of us. 60 bpm is perhaps most common. Some people can handle 50 bpm. 40 bpm is pushing it for all but a few.

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No reason to worry unless you experience dizziness, light-headedness or other negative symptoms. Hypothyroidism may cause lower heart rate, so you may check your Thyroid function tests. Some people just have low RHR.

As I mentioned in an earlier post, my RHR was typically 45 early in the morning. Funny thing is, I felt very relaxed and at ease with a low HR. After the ablation, when my HR went up to 65-ish, it felt like my heart was racing and I definitely didn’t like it. After 5 months I’m still not used to it. The cardiologist says I was at increased risk of stroke and Alzheimer’s. But I felt better…go figure.

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Here’s a reason to work on a lower RHR.

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Safe to assume that unmedicated lower RHR is a reflection of good cardiovascular health, but I don’t think that article really says anything?
Causation vs correlation?
If faster HR damages valves then what does exercise do?

It’s a fair question. There is some evidence that excessive high intensity exercise can be damaging. But it is clear that exercise in general is good. Exercise strengthens (and grows) the heart. A strong heart pushes more blood per beat so needs fewer beats per minute at rest. There is probably a limit to how big and strong the heart can become, so there is a limit to how low the RHR can get. Stronger is better but lowering the RHR below some threshold (?) might not be worth the effort.

I see low RHR as a marker of good physical fitness and health. But not necessarily a cause of anything.

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Sure. A marker of having a good fitness level means you can focus on problems elsewhere. It’s got to be similar to having optimal eGFR or hba1c. Keep doing what your doing. But if the marker is not optimal, then it must indicate something could be better. With limited resources, we have to pick what we work on and leave out. A high RHR would be a great place to invest. A low RHR is good…getting it lower still might be better but the payoff probably isn’t high.

It can indicate that, but with aging the difference between the systolic and diastolic is often more of an indicator of the stiffness of the arteries, in which case higher is worse.

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My low sleeping HR has fallen into to 30’s recently. I’ve had a low of 34 bpm twice now. This coincides with me feeling much stronger and having more power on the bike (post statin). And sleeping better. Maybe I’m recovering better?

I have been doing cardio in a hot garage lately. It’s been very tiring but I only do it 2x/week. Would that lower my sleeping HR by 6bpm? Lowest I’ve ever seen (didn’t track HR before 40 yo).

Strange.

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