The practical approach is first to not get very excited about any of this. I appreciate their formula for predicting age … but it’s not outcome based (sadly). If you are 12 years younger on their approach, does this mean you have the same years of life left as a typical 38 yr old? That’s what one would assume, but the data isn’t there to support these outcome measures.
With HsCRP, Monocytes, Ferritin all can go up with a chronic infection, inflammation, autoimmune disease, acute infections also. Sirolimus, statins, Curcumin, Omega 3’s all help - but an evaluation for an underlying condition may be reasonable, as much as the abnormalities are minor. Could there actually be iron overload at a low level? Possibly, but ferritin is also an inflammatory marker.
Free T being low - worth a recheck and if so - consideration of discussion with a physician whether to address this.
MCV not exciting - and still normal - typically things that increase this include alcohol use, B12 or Folate deficiency.
IGF-1 being up - most common issues are too much protein in the diet, too much growth hormone, low cortisol. Rapamycin typically drives this down.
DHEA-S - can address with direct supplementation, but sometimes improves simply with normalizing testosterone. I’d typically check a 4 point salivary cortisol on someone with this (ZRT offers this).
That would be my quick general approach on this - but as usual - don’t implement anything based on this general discussion without consulting your doctor.