Your Gemini response mentioned:
There is some evidence that carnosine (a dipeptide supplement) can inhibit AGE formation.
So I asked CGPT: “Can you identify and summarize all that evidence?”
Short answer: there is substantial mechanistic, in-vitro, and animal evidence that carnosine inhibits AGE formation; human data are suggestive but still thin and heterogeneous.
Below is a structured map of the evidence rather than a random paper list.
It wasn’t clear in the first response on the amounts of either hyaluronic acid or silica, so I asked Gemini to elaborate further:
| Ingredient | Role in ECM | Validated Daily Dose Range | Key Considerations |
|---|---|---|---|
| G - Glycine | Building Block(Precursor for Collagen) | 3,000 – 5,000 mg(3–5 grams) | This high dose compensates for the body’s limited ability to produce enough glycine for optimal collagen synthesis. |
| H - Hyaluronic Acid | Hydration & Lubrication(Signaling Molecule) | 120 – 300 mg | Look for products with low-to-medium molecular weight HA, as it has better oral bioavailability and signaling capacity for internal tissues. |
| S - Silica | The Cross-Linker(Essential Co-factor for Collagen) | 10 – 40 mg(Elemental Silicon) | This is the elemental Silicon content, not the weight of the extract. Aim for Bamboo Extract standardized to a high percentage of silica (often found in capsules labeled as 200mg of extract yielding 10-40mg of elemental silica). |
If you are looking to specifically target internal connective tissue (like fascia and tendons), combining these dosages with the resistance training and anti-glycation diet mentioned previously will create the most scientifically comprehensive approach.
and from CGPT:
If you were hoping to use canned bamboo shoots as a reliable dietary source of silica to support connective tissue, skin, bone, etc., you should remain skeptical: while bamboo shoots (fresh) do contain some measurable silicon, there is no robust data confirming how much silica survives through canning, or how bioavailable it is when you eat it.
If silica intake is a priority for you, relying on “bamboo-shoot as food” seems too uncertain. Instead, if you’re considering silica supplementation (for skin, bone, connective tissue), a dedicated bamboo-derived silica extract might be a more controllable alternative — though even then, absorption/bioavailability data should be verified.
Full response: ChatGPT - Silica levels in bamboo shoots
and there are lots of bamboo shoot silica extract products out there (who knew?)
