52% lower risk of ASCVD mortality with regular aspirin use

Quality Asprin Study (American Journal of Preventive Cardiology, April 2024:
52% lower risk of ASCVD mortality with regular aspirin use (HR=0.48, 95% CI: 0.28-0.83) << That’s an impressive result!
https://www.sciencedirect.com/science/article/pii/S2666667724000424

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regular aspirin use was associated with a 52% lower risk of ASCVD mortality among individuals with elevated Lp(a)

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Yet no all cause effect and higher CVD for high dose aspirin users in this study Low- or high-dose preventive aspirin use and risk of death from all-cause, cardiovascular disease, and cancer: A nationally representative cohort study - PMC

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FWIW

This was retrospective association study?

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“What’s it all about when you sort it out, Alfie?”

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