Nuts are loaded with antioxidants, especially raw walnuts.
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22 pills now for 2022
Dr. M. Thimineur stated in age-reversal forum today:
"
30mg every two weeks for about one year. Experimented with 90mg every 6 weeks (30mg with fresh grapefruit) for about 6 months before, and weekly dose of 15mg prior to that. People that I have placed on a sirolimus regimen generally do fine on either weekly or biweekly dosing. Weekly dose is calculated at .18mg/kg and biweekly is just double that. Bloodwork in all patients has been fine except a bump in total cholesterol. Even on 90mg every 6 weeks I never had side effects."
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That is certainly levels of intake considerably higher than anything I have previously read about. Twice .18mg/kg comes out to 27 mg biweekly for a 165 pound person. I wonder how many people he has had do that without significant negative side effects.
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This is what Dr. Thimineur said “I have practiced interventional pain management for nearly 30 years and an early adopter of rapamycin and metformin for personal age reversal – doing great. I have prescribed rapamycin to about 50 chronic pain patients representing the exact opposite of a typical self experimenter in terms of health.”
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anyone have a website for Dr. Thimineur?
Also he has communicated with me at the the age reversal forum.
Now Dr. Thimineur is in the forefront of Rapamycin dosage.
“The biweekly dose is 30mg sirolimus without grapefruit juice. Every 6 week dosing of 90mg was 30mg sirolimus dosed with grapefruit juice. There are GI side effects dosing over 40-50mg at once so grapefruit juice is required to avoid these side effects when taking more than that amount.”
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Thanks. Very interesting. Not a lot on his website about rapamycin unless I’m missing it. Seems he is going rogue with the high doses compared to other docs.
I think it is more useful to report in mg/kg rather than a specific number of mg taken. Body sizes are quite variable.
I am taking 0.277 mg/kg at the moment with no side effects every two weeks
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Been on Rapa since 2017. Have taken all doses orally. Now take 30 mg. twice a month. No problems. 76 yo male in good health. Intermuscular injection is the wave to the future. Less side-effects and greater availability in the brain inhibiting MTor. Skip Gut and Liver. Much smaller dose than oral. Have not done it yet, but just a matter of time. Once a person gets past a certain age, you have to take calculated Risks or else.
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