# \#senescence

**URL:** https://www.rapamycin.news/tag/senescence/57.md

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## [Targeting immune senescence and systemic aging](https://www.rapamycin.news/t/targeting-immune-senescence-and-systemic-aging/5717)

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**Author:** [@Caveatmtor](https://www.rapamycin.news/u/Caveatmtor)\
**Replies:** 8\
**Last updated:** [August 15, 2026, 12:31am UTC](https://www.rapamycin.news/t/targeting-immune-senescence-and-systemic-aging/5717 "2026-08-15T00:31:08Z")

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Targeting cellular senescence to extend healthspan | Prof Paul Robbins An aged immune system drives senescence and ageing of solid organs Abstract Ageing of the immune system, or immunosenescence, contributes to the morbidity and mortality of the elderly1,2. To define the contribution of immune system ageing to organism ageing, here we selectively deleted Ercc1, which encodes a cr…

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## [How does Rapamycin increase healthspan and lifespan](https://www.rapamycin.news/t/how-does-rapamycin-increase-healthspan-and-lifespan/5057)

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**Author:** [@Biohacker2020](https://www.rapamycin.news/u/Biohacker2020)\
**Replies:** 2\
**Last updated:** [January 17, 2023, 1:11am UTC](https://www.rapamycin.news/t/how-does-rapamycin-increase-healthspan-and-lifespan/5057 "2023-01-17T01:11:33Z")

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I know it works via MTor pathway, but I’m curious if there’s more. I also know it removes and reprograms senescence cells and lowers IGF. So would testosterone be contraindicated? Is senescence cells main driver of healthspan and healing factors?

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## [Methionine Is Not the Only "Problem" Amino Acid](https://www.rapamycin.news/t/methionine-is-not-the-only-problem-amino-acid/2550)

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**Author:** [@EnrQay](https://www.rapamycin.news/u/EnrQay)\
**Replies:** 7\
**Last updated:** [August 8, 2022, 7:21am UTC](https://www.rapamycin.news/t/methionine-is-not-the-only-problem-amino-acid/2550 "2022-08-08T07:21:20Z")

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Glutamine, which is synthesized in the body from dietary glutamate, prevents the destruction of senescent cells. BTW, this is a great account to follow for the latest anti-aging and health research.