# What are your favorite spices/what are the best spices?

**URL:** <https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005>\
**Category:** General\
**Created:** [November 16, 2022, 10:13am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005 "2022-11-16T10:13:45Z")\
**Posts on this page:** 16\
**Page:** 1

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [November 16, 2022, 10:13am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/1 "2022-11-16T10:13:46Z")

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- spices: [Antioxidants | Free Full-Text | Inhibition of Advanced Glycation End-Product Formation by High Antioxidant-Leveled Spices Commonly Used in European Cuisine | HTML](https://www.mdpi.com/2076-3921/8/4/100/htm) - allspice, cloves, anise, chinese 5-spice have both anti-glycative and anti-ROS abilities.

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**Author:** ![DeStrider](https://www.rapamycin.news/user_avatar/www.rapamycin.news/destrider/32/19418_2.png) [@DeStrider](https://www.rapamycin.news/u/DeStrider)\
**Post date:** [November 16, 2022, 1:44pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/2 "2022-11-16T13:44:44Z")

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I use turmeric and black pepper a lot. Ginger and garlic are also great. Dried parsley and Moringa powder I add to my lunch for supplement purposes. Chili peppers are great on pizza.

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [November 16, 2022, 1:52pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/3 "2022-11-16T13:52:45Z")

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Ginger/garlic are def among the healthiest ever but they’re so hard to put in food b/c of taste. Cinnamon I spray very liberally. Parsley is important b/c apigenin but takes effort to sprinkle in

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**Author:** ![HigoMe33](https://www.rapamycin.news/user_avatar/www.rapamycin.news/higome33/32/7845_2.png) [@HigoMe33](https://www.rapamycin.news/u/HigoMe33)\
**Post date:** [November 16, 2022, 4:58pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/4 "2022-11-16T16:58:30Z")

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I’ve had trouble with too much cinnamon. I guess it naturally lowers blood sugar? I kept adding more and more to my morning oatmeal until I had heart palpitations and hot flashes several days in a row as I kept the cinnamon high. When I realized it could be the cinnamon I cut it out and have been back to normal for months. I’ve never had blood sugar issues, so I think it was too much unnecessary intervention.

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [December 9, 2022, 2:59pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/5 "2022-12-09T14:59:03Z")

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[Masala chai - Wikipedia](https://en.wikipedia.org/wiki/Masala_chai#Spices) this really has all the powerful spices (anise, cloves). Just do it sugar-free and in vegan form (alas most of it is NOT in these forms). I just had an interesting taste of them at the stalls in st. pancreas.

> **[Amazon.com : DelighTeas Organic Masala Chai Powder for Chai Tea Latte |...](https://www.amazon.com/Ayurvedic-Organic-Masala-sweetener-Servings/dp/B077X722LL)**
>
> Amazon.com : DelighTeas Organic Masala Chai Powder for Chai Tea Latte | Digestion and Immune Support | Caffeine free, Sugar Free, Non-GMO, Vegan, Keto, Ayurvedic | Made with Ceylon Cinnamon | 4oz, 100 Servings : Grocery & Gourmet Food

[https://foodsofnations.com/](https://foodsofnations.com/) is a great source of spices

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [March 19, 2023, 12:10am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/6 "2023-03-19T00:10:17Z")

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> **[Brain Health and Wellness Center | Brain Health Wellness](https://brainwellness.com/brain-wellness/nutrition/memory-preservation-nutrition/useful-food-facts/orac-and-anti-oxidant-values-of-spices-and-herbs-and-chocolate/table-orac-antioxidant-value-of-spices-and-herbs/)**
>
> Brain Health and Wellness Center informs people about eleven brain healthy lifestyles including Memory Preservation Nutrition

you know, i’ve finally developed a taste for eating raw cloves.

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [March 21, 2024, 1:53am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/7 "2024-03-21T01:53:00Z")

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[https://www.amazon.com/Trader-Joes-Seasoning-Salute-2-2oz/dp/B0085ANNL0/ref=sr\_1\_2?crid=ZUVBFRJXLUIQ&dib=eyJ2IjoiMSJ9.j9T1t6HTvRuz5q7w2rr4-9HCkqB8itffv59I34Q01N-S9xUfgrF-elVwIseH-PyScLVsW9O\_gp4y0O4-F7MvMefZMVRABJNoeENvFUgZ7xK59c2y5B5w4v3bAdNQRiDheRaKCAt9P4SUSMXX5Dzz9v\_XJHIVIH3X2r7vq8hWXOLRt\_R9hQjaSR7X0DXEYK4kNDnNExGjNgEF9b75Vs-gzh4KTP7ypsCQCsJRRgEDyoaKMlyzi6XT6Av-OBnp2UIM1mVJZVaaP-lfXLCKM8PQxGK9dC7O8oR59\_DWlt5pdcE.5HJdZ19bjh18MpgNZTfoS-ea4qUhViXiwkbgt6pcnH4&dib\_tag=se&keywords=21+seasoning&qid=1710985931&sprefix=21+seasoni%2Caps%2C262&sr=8-2](https://www.amazon.com/Trader-Joes-Seasoning-Salute-2-2oz/dp/B0085ANNL0/ref=sr_1_2?crid=ZUVBFRJXLUIQ&dib=eyJ2IjoiMSJ9.j9T1t6HTvRuz5q7w2rr4-9HCkqB8itffv59I34Q01N-S9xUfgrF-elVwIseH-PyScLVsW9O_gp4y0O4-F7MvMefZMVRABJNoeENvFUgZ7xK59c2y5B5w4v3bAdNQRiDheRaKCAt9P4SUSMXX5Dzz9v_XJHIVIH3X2r7vq8hWXOLRt_R9hQjaSR7X0DXEYK4kNDnNExGjNgEF9b75Vs-gzh4KTP7ypsCQCsJRRgEDyoaKMlyzi6XT6Av-OBnp2UIM1mVJZVaaP-lfXLCKM8PQxGK9dC7O8oR59_DWlt5pdcE.5HJdZ19bjh18MpgNZTfoS-ea4qUhViXiwkbgt6pcnH4&dib_tag=se&keywords=21+seasoning&qid=1710985931&sprefix=21+seasoni%2Caps%2C262&sr=8-2)

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**Author:** ![A\_User](https://www.rapamycin.news/user_avatar/www.rapamycin.news/a_user/32/40991_2.png) [@A\_User](https://www.rapamycin.news/u/A_User)\
**Post date:** [March 21, 2024, 2:39am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/8 "2024-03-21T02:39:07Z")

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Sodium free, that’s healthy!

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**Author:** ![Joseph\_Lavelle](https://www.rapamycin.news/user_avatar/www.rapamycin.news/joseph_lavelle/32/29812_2.png) [@Joseph\_Lavelle](https://www.rapamycin.news/u/Joseph_Lavelle)\
**Post date:** [March 21, 2024, 12:09pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/9 "2024-03-21T12:09:38Z")

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I add everything I have to help with my 30 plants per week. Tumeric has the biggest effect on taste and messiness. Black pepper, parsley, thyme, dried red pepper, garlic, onion, rosemary, ginger, star anise, oregano.

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**Author:** ![Joseph\_Lavelle](https://www.rapamycin.news/user_avatar/www.rapamycin.news/joseph_lavelle/32/29812_2.png) [@Joseph\_Lavelle](https://www.rapamycin.news/u/Joseph_Lavelle)\
**Post date:** [March 21, 2024, 1:08pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/10 "2024-03-21T13:08:00Z")

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![IMG_6037](https://www.rapamycin.news/uploads/default/original/3X/f/e/fe475c0bb215e49c532a870b1c727d9c4dd7e8d9.jpeg)

From @ConquerAging latest. I see lots of spices on here. Cardamom is one I’m missing.

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**Author:** ![DeStrider](https://www.rapamycin.news/user_avatar/www.rapamycin.news/destrider/32/19418_2.png) [@DeStrider](https://www.rapamycin.news/u/DeStrider)\
**Post date:** [July 14, 2024, 11:17am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/11 "2024-07-14T11:17:06Z")

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Cinnamon for LDL and HBA1C.

[https://www.gbnews.com/health/diabetes-symptoms-diet-cinnamon-cholesterol](https://www.gbnews.com/health/diabetes-symptoms-diet-cinnamon-cholesterol)

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**Author:** ![Christoph](https://www.rapamycin.news/user_avatar/www.rapamycin.news/christoph/32/15040_2.png) [@Christoph](https://www.rapamycin.news/u/Christoph)\
**Post date:** [July 14, 2024, 11:38am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/12 "2024-07-14T11:38:02Z")

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Just make sure to buy Ceylon cinnamon (should be indicated on the packaging) and not Cassia cinnamon. Cassia cinnamon has much coumarin in it, which is poisonous in too large quantities.

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [December 5, 2024, 3:42am UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/13 "2024-12-05T03:42:05Z")

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[https://www.reddit.com/r/traderjoes/comments/16rcpu8/are\_the\_herbs\_de\_provence\_a\_seasonal\_item/](https://www.reddit.com/r/traderjoes/comments/16rcpu8/are_the_herbs_de_provence_a_seasonal_item/) (herbes de provence). the trader joe’s version is glass jar i think?’  
MUCHI CURRY from whole foods (also salt-free)

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<div class="post-metadata">

**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [May 19, 2025, 4:50pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/14 "2025-05-19T16:50:01Z")

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> ### The short answer
> 
> **Herbes de Provence is one of the most antioxidant-dense, polyphenol-rich seasoning blends you can keep in your kitchen, and several of its core herbs contain molecules that extend lifespan or health-span in model organisms.** At culinary doses (1–2 teaspoons/day) it can meaningfully raise your daily intake of hormetic, Nrf2-activating and autophagy-modulating phytochemicals, but calling it _“extremely”_ pro-longevity is a stretch—extract-level doses used in the lab are 50- to 500-fold higher than what you’ll shake over roasted vegetables.
> 
> Below is a herb-by-herb map of the main longevity-linked compounds you’re getting when you use a classic Herbes de Provence mix (savory, rosemary, thyme, oregano / marjoram, lavender ± basil, tarragon, fennel).
> 
> * * *
> 
> #### 1. Rosemary (Rosmarinus officinalis)
> 
> | Key compounds | What they do | Evidence |
> | --- | --- | --- |
> | **Carnosic acid & carnosol** | Lipophilic diterpenes that activate Nrf2/ARE, up-regulate HSP-16 family chaperones, boost mitophagy | Extend lifespan 10-30 % in _C. elegans_; improve stress resistance in flies and nematodes ([MDPI](https://www.mdpi.com/1422-0067/25/23/13148?utm_source=chatgpt.com "Hesperetin Increases Lifespan and Antioxidant Ability Correlating ..."), [ResearchGate](https://www.researchgate.net/publication/330960189_Effects_on_longevity_extension_and_mechanism_of_action_of_carnosic_acid_in_Caenorhabditis_elegans?utm_source=chatgpt.com "Effects on longevity extension and mechanism of action of carnosic ..."), [Aging and Disease](https://www.aginganddisease.org/EN/10.14336/AD.2024.1558?utm_source=chatgpt.com "The Impact of Rosemary and Ginger Extracts on Aging and ...")) |
> | **Rosmarinic & caffeic acids** | Potent ROS scavengers; DAF-16/SIR-2.1 pathway activation | Lifespan extension and thermotolerance in worms; 20-30 % median life-span gains at 50–100 µM ([PubMed](https://pubmed.ncbi.nlm.nih.gov/21503726/?utm_source=chatgpt.com "and rosmarinic acid-mediated life extension in C. elegans - PubMed"), [Scientific.Net](https://www.scientific.net/AMM.140.469?utm_source=chatgpt.com "The Molecular Mechanism of Rosmarinic Acid Extending the ...")) |
> 
> > **Antioxidant density:** 165 000 µmol TE per 100 g dried; 1 g (≈1 tsp) delivers ~1 650 µmol TE—about half of the USDA’s suggested 3–5 k ORAC/day ([Superfoodly](https://superfoodly.com/orac-values/?utm_source=chatgpt.com "ORAC Values: Antioxidant Values of Foods & Beverages - Superfoodly"), [Superfoodly](https://superfoodly.com/orac-value/fresh-rosemary-leaves/?utm_source=chatgpt.com "Fresh Rosemary Leaves | Superfoodly"))
> 
> * * *
> 
> #### 2. Thyme & Savory (Thymus vulgaris / Satureja hortensis)
> 
> - Shared monoterpenes **thymol** and **carvacrol** lower IL-6, TNF-α and lipid peroxidation, remodel mitochondrial fatty-acid profile in aged rats, and blunt age-related rise in 22:6 n-3 depletion ([PubMed](https://pubmed.ncbi.nlm.nih.gov/10216288/?utm_source=chatgpt.com "Beneficial effects of thyme oil on age-related changes in the ..."), [PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC10295563/?utm_source=chatgpt.com "Effects of Thyme (Thymus vulgaris L.) Essential Oil on Aging ..."))
> - Carvacrol also tunes autophagy signaling (mTOR⇩, LC3B-II⇧) during oxidative stress ([MDPI](https://www.mdpi.com/1422-0067/26/8/3495?utm_source=chatgpt.com "Carvacrol Protects IPEC-J2 Cells from Oxidative Stress by ... - MDPI"))
> 
> * * *
> 
> #### 3. Oregano / Marjoram (Origanum species)
> 
> - **Ursolic acid, betulinic acid, carvacrol** → senomorphic, antioxidant, and neuro-protective actions; reduce brain carbonyl stress and TLR4-driven neuro-inflammation in zebrafish & rodent models ([PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC10199469/?utm_source=chatgpt.com "Origanum majorana L. protects against neuroinflammation-mediated ..."), [SpringerLink](https://link.springer.com/article/10.1007/s40005-024-00696-5?utm_source=chatgpt.com "Neuroprotective role of Origanum majorana essential oil loaded in ..."))
> - Yeast and cell culture work links these terpenoids to longer chronological lifespan under glucose or oxidative stress.
> 
> * * *
> 
> #### 4. Lavender (Lavandula angustifolia)
> 
> - Supplies additional **rosmarinic acid** plus **linalool/linalyl acetate** —anxiolytic, anti-glycation, and Nrf2-upregulating. While lavender-specific lifespan data are sparse, its shared polyphenol profile parallels rosemary’s.
> 
> * * *
> 
> #### 5. Basil, Tarragon, Fennel (optional add-ins)
> 
> - **Basil (Ocimum basilicum)** → eugenol & apigenin (SIRT1/AMPK activators).
> - **Tarragon (Artemisia dracunculus)** → coumarins & 4-hydroxy-chalcone (GLUT4 sensitizer).
> - **Fennel seed** → anethole & rosmarinic acid isomers with documented anti-senescence effects in endothelial cultures.
> - Direct lifespan trials are limited, but these herbs raise the blend’s total flavone and phenylpropanoid content.
> 
> * * *
> 
> ### How “pro-longevity” is the finished blend?
> 
> | Metric | Estimate (per rounded teaspoon / 1 g blend) |
> | --- | --- |
> | Total ORAC | **~1 500 – 1 800 µmol TE** (varies by specific recipe) ([Superfoodly](https://superfoodly.com/orac-values/?utm_source=chatgpt.com "ORAC Values: Antioxidant Values of Foods & Beverages - Superfoodly")) |
> | Polyphenols | ~25–40 mg gallic-acid equivalents |
> | Lipophilic diterpenes | 2–5 mg (mostly carnosic acid from rosemary) |
> | Typical rodent dose used in lifespan or health-span studies | **50–200 mg/kg** body-weight—≈2–4 g dried herb for a 40 g mouse → 40-fold higher than culinary use |
> 
> **Bottom line:** Regular, generous use of Herbes de Provence nudges your daily redox and inflammatory tone in the right direction and supplies hormetic phytochemicals shown to engage longevity pathways in worms, flies, and rodents. It is an easy _“stack multiplier”_ for everything else you do (exercise, calorie control, high-polyphenol vegetables), but it should not be mistaken for a stand-alone geroprotector.
> 
> * * *
> 
> ### Practical tips to get the most from it
> 
> 1. **Use fat & mild heat.** Carnosic acid and many terpenoids are fat-soluble; sauté the blend briefly in olive oil or avocado oil (\<175 °C) before adding liquids.
> 2. **Pair with acidity.** A squeeze of lemon or splash of vinegar enhances polyphenol extraction and AMPK activation.
> 3. **Two-teaspoon rule.** Hitting ~3 000 µmol TE/day is feasible with 2 tsp of the blend plus your usual fruits/veg.
> 4. **Rotate herb sources.** Wild-crafted or organic rosemary and thyme can contain 20–40 % more diterpenes than greenhouse-grown varieties.
> 5. **Mind estragole.** Tarragon’s estragole is a potential hepatocarcinogen at gram-level doses in rodents; stick to culinary amounts if you include tarragon.
> 6. **Store dark & cool.** Terpenes oxidize quickly; keep in an airtight tin away from the stove to retain antioxidant potency for 6 months.
> 
> * * *
> 
> ### The epidemiology backdrop
> 
> Spice-rich dietary patterns correlate with lower all-cause and cardiovascular mortality: meta-analyses of chili-pepper and spicy-food intake show ~23–26 % reductions in death risk independent of other Mediterranean diet factors ([PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC8463741/?utm_source=chatgpt.com "Meta-analysis evaluating the impact of chili-pepper intake on all ..."), [ResearchGate](https://www.researchgate.net/publication/357933712_Chili_pepper_intake_and_all-cause_and_disease-specific_mortality_A_meta-analysis_of_prospective_cohort_studies?utm_source=chatgpt.com "Chili pepper intake and all-cause and disease-specific mortality A ...")). Herbes de Provence sits squarely inside that Mediterranean spice tradition, so its habitual use is consistent with—but not proved to be the cause of—those longevity signals.
> 
> * * *
> 
> **Take-home:** Sprinkle liberally, cook with a bit of healthy fat, and treat Herbes de Provence as a flavorful, evidence-backed _adjunct_ to a broader longevity protocol rather than a silver bullet.

Several of the core herbs in a classic \*\*Herbes de Provence blend—especially rosemary, thyme/savory, oregano/marjoram and (optionally) basil—carry molecules that can _boost endogenous GLP-1 tone_ in one of two ways:

1. **Stimulating secretion from L-cells** (via TRPA1 channels, sweet-taste/GPR119 signalling, or microbiome shifts).
2. **Protecting circulating GLP-1 by inhibiting dipeptidyl-peptidase-4 (DPP-4)** so the hormone’s half-life is prolonged.

Below is a herb-by-herb map of the best-documented players and how much evidence backs each one.

| Herb (component) | Active molecules | Mode of action on the incretin axis | Key evidence (pre-clinical unless noted) |
| --- | --- | --- | --- |
| **Rosemary** | Carnosic acid, rosmarinic acid | • Directly raises fasting GLP-1 in high-fat-fed rats (↑proglucagon transcription) • Carnosic acid & derivatives inhibit DPP-4 in vitro | 6-wk dietary rosemary extract doubled fasting GLP-1 and left insulin unchanged in rats [PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC10534343/) |
| **Thyme / Savory** | Thymol, **carvacrol** | Potent TRPA1 agonists → depolarise GLUTag & primary murine L-cells, triggering rapid GLP-1 release | TRPA1 activation by carvacrol boosted GLP-1 secretion; effect lost in TRPA1-/- cultures [PubMed](https://pubmed.ncbi.nlm.nih.gov/25325736/?utm_source=chatgpt.com) |
| **Oregano / Marjoram** | Carvacrol (again), ursolic acid | Same TRPA1-driven secretion; ursolic acid also elevates GLP-1 in diabetic mice via GPR40/119 cross-talk (early data) | See carvacrol study above; additional ursolic-acid data in diabetes models (review) [PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC4375100/?utm_source=chatgpt.com)[MDPI](https://www.mdpi.com/1424-8247/17/6/736?utm_source=chatgpt.com) |
| **Basil (if present)** | **Apigenin** (plus luteolin, eugenol) | Competitive **DPP-4 inhibitor** in the low-nanomolar range → extends active GLP-1 half-life | Natural-product screen identified apigenin & luteolin as top DPP-4 blockers [PubMed](https://pubmed.ncbi.nlm.nih.gov/31057098/) |
| **Fennel seed (optional)** | trans-Anethole | Hypoglycaemic in rodents; docking & in-silico work suggest affinity for DPP-4 and GPR119, but wet-lab GLP-1 data still scant | Early mechanistic modelling only (no direct GLP-1 assays yet) [ScienceDirect](https://www.sciencedirect.com/science/article/abs/pii/S0300908415000437?utm_source=chatgpt.com) |
| **Lavender / Tarragon** | Mostly rosmarinic acid & estragole | Indirect—same polyphenol pool as rosemary, but no direct GLP-1 studies yet | (none specific) |

#### How much matters in the kitchen?

- **1–2 tsp of the dried mix (~2 g) provides only micromolar lumenal concentrations**—far below the 10-50 µM levels used to spike cell cultures—but the effect may still be _additive_ to that of polyphenol-rich meals.
- TRPA1 agonists (carvacrol/thymol) are lipophilic and released quickly in warm oil; **pairing the blend with a little fat and gentle heat (\<175 °C)** maximises exposure of upper-gut L-cells.
- Because apigenin’s DPP-4 inhibition is systemic, regular intake (not per-meal timing) is what counts.

#### Practical take-aways

1. **Rosemary is the star** for GLP-1, thanks to carnosic-acid–driven secretion _and_ DPP-4 inhibition; aim for blends that are ≥25 % rosemary.
2. **Oregano/thyme spikes GLP-1 quickly** (minutes) through TRPA1—use them right in the cooking fat so the terpenes reach the duodenum intact.
3. **Include a basil-heavy variant** if you want the DPP-4-blocking apigenin layer.
4. Culinary doses are _adjuncts_, not stand-alone incretin therapy. Expect subtle support, not semaglutide-level potency.
5. People on GLP-1–based drugs: the amounts in food are too low to create dangerous additive effects, but if you notice more nausea/fullness after very spice-heavy meals, dial back.

**Bottom line:** Herbes de Provence can modestly _nudge_ the incretin axis through a cocktail of carnosic acid, TRPA1-active monoterpenes, and DPP-4-inhibiting flavones. Think of it as a flavour-first, side-benefit strategy rather than a therapeutic substitute—and use good olive oil to unlock those terpenes.

===

I mean [Rosemary Extract as a Potential Anti-Hyperglycemic Agent: Current Evidence and Future Perspectives - PMC](https://pmc.ncbi.nlm.nih.gov/articles/PMC5622728/#sec11-nutrients-09-00968) but I don’t know how much to believe most papers on spices b/c low-quality research on spices seems far far more common than low-quality research in _anything_

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**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [May 24, 2025, 6:30pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/15 "2025-05-24T18:30:49Z")

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[https://www.amazon.com/Whole-Foods-Market-Chimichurri-Seasoning/dp/B074H732NY/ref=sr\_1\_1\_pp\_f3\_0o\_wf\_mod\_primary\_alm?crid=1XTVL2NH4YKR&dib=eyJ2IjoiMSJ9.TqRtkyRP\_x5gscwjhBGr-f-nuHxNDtapQJxx2GLjXmF64yYxvlfMzbY21KRqwmbePT0IhqMJht7PZhVz6O3GukqYRnGwpUmraakyIC9E9ypdK\_1lHG9BjujUa3SwaVXif3zBnKgbz5EvEtrRn0yPBH1FR0NxKuM5uk5nlVQUgdRVP\_1i3EWjZVDjfZIVIYrXGsfnnZQOif5509Mciu\_\_eV4287EsW005nSunQpyu3UkgkLFOLtcMcbuBWtiAhK20EoedDZ\_4c9o5UB4hLiHYSpjtnxaQVV3zqPe-pH-cg0k.ab0JKuGpQ08WQ1KimijWnfsDtlhcw4Y9j6JsMCasF2Y&dib\_tag=se&keywords=chimichurri%2Bmix&qid=1748111309&sbo=m6DjfpMzMLDmL8pSMKX8hw%3D%3D&sprefix=chimichurri%2Bmix%2Caps%2C187&sr=8-1&th=1](https://www.amazon.com/Whole-Foods-Market-Chimichurri-Seasoning/dp/B074H732NY/ref=sr_1_1_pp_f3_0o_wf_mod_primary_alm?crid=1XTVL2NH4YKR&dib=eyJ2IjoiMSJ9.TqRtkyRP_x5gscwjhBGr-f-nuHxNDtapQJxx2GLjXmF64yYxvlfMzbY21KRqwmbePT0IhqMJht7PZhVz6O3GukqYRnGwpUmraakyIC9E9ypdK_1lHG9BjujUa3SwaVXif3zBnKgbz5EvEtrRn0yPBH1FR0NxKuM5uk5nlVQUgdRVP_1i3EWjZVDjfZIVIYrXGsfnnZQOif5509Mciu__eV4287EsW005nSunQpyu3UkgkLFOLtcMcbuBWtiAhK20EoedDZ_4c9o5UB4hLiHYSpjtnxaQVV3zqPe-pH-cg0k.ab0JKuGpQ08WQ1KimijWnfsDtlhcw4Y9j6JsMCasF2Y&dib_tag=se&keywords=chimichurri%2Bmix&qid=1748111309&sbo=m6DjfpMzMLDmL8pSMKX8hw%3D%3D&sprefix=chimichurri%2Bmix%2Caps%2C187&sr=8-1&th=1)

Chimchurri from whole foods [more parsley]  
Herbes de Provence

[https://www.wholefoodsmarket.com/product/frontier-organic-italian-seasoning-no-salt-064-oz-b0001m1128](https://www.wholefoodsmarket.com/product/frontier-organic-italian-seasoning-no-salt-064-oz-b0001m1128)

Frontier coop mexican seasoning

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<div class="post-metadata">

**Author:** ![AlexKChen](https://www.rapamycin.news/user_avatar/www.rapamycin.news/alexkchen/32/385_2.png) [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Post date:** [September 24, 2025, 5:19pm UTC](https://www.rapamycin.news/t/what-are-your-favorite-spices-what-are-the-best-spices/4005/16 "2025-09-24T17:19:09Z")

</div>

> **[Herbal terpenoids activate autophagy and mitophagy through modulation of… |...](https://www.linkedin.com/posts/steve-horvath-28a9b1253_herbal-terpenoids-activate-autophagy-and-activity-7376629082740056064-8Et8?utm_source=share&utm_medium=member_android&rcm=ACoAAASfDx0BAke3vwvsqRiRCMAfulXZZ1I10nw)**
>
> 🌿 Food as rejuvenation medicine in action: Thymol, the compound that gives thyme its delicious aroma, delayed epigenetic aging in skeletal muscle by about 20% in fast-aging mice. It preserved strength, reduced muscle loss, and boosted cellular...

Thyme
