# Raised Lipids on Rapa **URL:** \ **Category:** General\ **Created:** [February 23, 2023, 1:33pm UTC](https://www.rapamycin.news/t/raised-lipids-on-rapa/5838 "2023-02-23T13:33:07Z")\ **Posts on this page:** 1\ **Showing post:** 28
**Author:** ![JuanDaw](https://www.rapamycin.news/user_avatar/www.rapamycin.news/juandaw/32/5311_2.png) [@JuanDaw](https://www.rapamycin.news/u/JuanDaw)\ **Post date:** [October 30, 2023, 11:05pm UTC](https://www.rapamycin.news/t/raised-lipids-on-rapa/5838/28 "2023-10-30T23:05:34Z")
That was discussed in the two threads below: > [@Yamu Xu co-founder of Lifereversal](https://www.rapamycin.news/t/yamu-xu-co-founder-of-lifereversal/4743): > > Is any one familiar with his work? He is taking supplements I have not heard of here is a excerpt from a post I found on Quora: Lithium salts have a side effect, which is that it damages the kidney . Is there a way to reduce the side effects of lithium salts?According to related research, N-Acetylcysteine ameliorates lithium-induced renal failure in rats. (I usually take lithium with glutathione, NAC, glycine and betaine to protect liver and kidney ) According to A triple drug combination targeting components of the nutrient-sensing network maximizes longevity, rapamycin treatment results in insulin resistance and dyslipidemia in patients and mice, and this disturbance manifests as hypertriglyceridemia in Drosophila. Lithium reversed this and the starvation resistance associated with rapamycin treatment. In this study, double combinations of lithium and rapamycin, lithium and trametinib, or rapamycin and trametinib produced a reproducibly greater lifespan extension than controls, on… > [@Anyone taking Trametinib?](https://www.rapamycin.news/t/anyone-taking-trametinib/9856/23): > > 2 g per day. Take note of the post of Livin, quoted below: > Do not take trametinib for longevity purposes. I worked on synthetic lethal chemo combinations in cancer at a startup for years. We tested this compound and it is not a good idea. The Erk pathway is very important for most epithelial cells. Stick to low risk acarbose and rapamycin combinations and do not consider trametinib. If you have melanoma or another type of solid tumor type then you could consider trametinib. Just trying to prevent you from causing long term damage. --- _[View the full topic](https://www.rapamycin.news/t/raised-lipids-on-rapa/5838)._