# Joanne Mannick Joining Altos Labs **URL:** \ **Category:** General\ **Created:** [August 6, 2025, 12:04am UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949 "2025-08-06T00:04:36Z")\ **Posts on this page:** 10\ **Page:** 1
**Author:** ![CronosTempi](https://www.rapamycin.news/user_avatar/www.rapamycin.news/cronostempi/32/2504_2.png) [@CronosTempi](https://www.rapamycin.news/u/CronosTempi)\ **Post date:** [August 6, 2025, 12:04am UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/1 "2025-08-06T00:04:36Z")
Joanne Mannick is joining Altos Labs as Chief Medical Officer. What does this mean for Tornado Therapeutics? Is she leaving the company she co-founded? > **[I am delighted to announce that I have joined Altos labs as Chief Medical...](https://www.linkedin.com/posts/joan-mannick-8089a614_i-am-delighted-to-announce-that-i-have-joined-activity-7358160560288395269-ISrA)** > > I am delighted to announce that I have joined Altos labs as Chief Medical Officer. It is a dream job for me to be able to work with the great scientists at Altos to find new ways to reverse disease through cellular rejuvenation. | 71 comments on... > **[Joan Mannick, MD](https://www.altoslabs.com/team/joan-mannick)** > > Dr. Joan Mannick is the Senior Vice President, Chief Medical Officer and Head of Product Development at Altos Labs. [https://www.tornado-tx.com/team](https://www.tornado-tx.com/team) ---
**Author:** ![A\_User](https://www.rapamycin.news/user_avatar/www.rapamycin.news/a_user/32/40991_2.png) [@A\_User](https://www.rapamycin.news/u/A_User)\ **Post date:** [August 6, 2025, 12:58am UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/2 "2025-08-06T00:58:24Z")
Interesting find, I’ve been following their work for a bit before. Altos seem to be doing the right thing, like with the IL-11 therapy, this is bullish overall. Though Kaeberlein wasn’t so happy with the failed drug, I don’t remember if it was ex ante. > [@CronosTempi](#): > > Is she leaving the company she co-founded? Looks to be that: > Joan brings extensive drug development expertise to Altos **including from her time** as the Chief Executive Officer and Co-Founder of Tornado Therapeutics. ---
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [August 6, 2025, 4:30am UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/3 "2025-08-06T04:30:59Z")
Strange… they must be shutting down Tornado. I can’t see it continuing without the founder and lead person for the company. I wonder what happened? Some failed phase 1 clinical studies? We need to learn more. ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [August 6, 2025, 6:26am UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/4 "2025-08-06T06:26:22Z")
[https://www.tornado-tx.com/team](https://www.tornado-tx.com/team) According to this She is still the CEO > **[Division of Corporations - Filing](https://icis.corp.delaware.gov/ecorp/entitysearch/namesearch.aspx)** > > Delaware Division of Corporations - Home Page Finds the company, but you need to pay to get any information. Her LinkedIn, however, has > **[Joan Mannick - Altos Labs | LinkedIn](https://www.linkedin.com/in/joan-mannick-8089a614/)** > > Experience: Altos Labs · Education: Harvard College · Location: Weston · 500+ connections on LinkedIn. View Joan Mannick’s profile on LinkedIn, a professional community of 1 billion members. Her ceasing at Tornado in August 2025. Clearly there is more to be heard. ---
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [August 6, 2025, 5:30pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/5 "2025-08-06T17:30:37Z")
Tornado is under the Cambrian Biopharma umbrella, and they still have the compounds listed under their pipeline list. it will be interesting to see if they delete them from the list, or do something else with these drug candidates: > **[Pipeline](https://www.cambrianbio.com/pipeline)** > > Cambrian is developing a wide array of new therapeutics, each targeting a biological driver of aging. We work with top-tier academic institutions to create Cambrian Pipeline Companies across the US and Europe. ![Screenshot 2025-08-06 at 10.44.19 AM](https://www.rapamycin.news/uploads/default/original/3X/4/3/43d0c86375a1f01143d173c035ec271a4bbf1e15.jpeg) ---
**Author:** ![CronosTempi](https://www.rapamycin.news/user_avatar/www.rapamycin.news/cronostempi/32/2504_2.png) [@CronosTempi](https://www.rapamycin.news/u/CronosTempi)\ **Post date:** [August 6, 2025, 5:34pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/6 "2025-08-06T17:34:38Z")
Well, the question is what happens with all the IP that Tornado developed or owns. Does Mannick have a piece of that? Does she bring it in with her to Altos? It’s entirely possible that this was one consideration fir Altos hiring her. Or does Tornado retain all IP and keeps soldiering on. ---
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [May 28, 2026, 7:40pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/7 "2026-05-28T19:40:48Z")
Quite a few changes at Altos… > ## Peter Walker left Altos Labs, Steve Horvath too > > I heard through the grapevine that key investigator Steve Horvath departed Altos a few months ago. > > [**Horvath’s LinkedIn**](https://www.linkedin.com/in/steve-horvath-28a9b1253/)page lists his work at Altos as having ended this February. I couldn’t find any listing for Horvath on the Altos Labs website either. An email to his former Altos email generated a reply saying he’s no longer there. > > Horvath is a leader in the area of epigenetic clocks. What’s next for him? It’s not 100% clear if he retains a UCLA appointment as a professor of Human Genetics and Biostatistics as he did before, but he’s still on the website and UCLA was listed as an affiliation on a paper just a few months ago. > > Wherever he ends up, I wish him well. > > Another Altos leader, [**Peter Walter,**](https://www.bizjournals.com/sanfrancisco/news/2026/04/17/aging-altos-labs-buck-institute-peter-walter-ucsf.html) recently left Altos Labs and joined the Buck Institute. > > Apparently quite a few others have left Altos as well. Source: [Did Altos Labs just reprogram itself to focus on AI? Peter Walter, Steve Horvath, & more departures - The Niche](https://ipscell.com/2026/05/did-altos-labs-just-reprogram-itself-to-focus-on-ai-peter-walter-steve-horvath-more-departures/) ---
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [August 17, 2026, 6:57pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/8 "2026-08-17T18:57:20Z")
Another major departure from Altos Labs: Morgan Levine… ![Screenshot 2026-08-17 at 11.55.46 AM](https://www.rapamycin.news/uploads/default/original/3X/c/f/cf9bc9264e3bae493a89deb2a3bdf907cb739cd8.jpeg) From: [Antonio Regalado on X: "Another high-profile recruit leaves Altos Labs. Of six notable hires, 1/2 half have departed (horvath, walter, levine.) 1/2 remain (belmonte, reik, serrano) To me, the phrase "i've made the decision to move on" signals difficulty/discontent, what do you think?" / X](https://x.com/antonioregalado/status/2089326111876317594?s=20) ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [August 17, 2026, 7:17pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/9 "2026-08-17T19:17:32Z")
I am not sure that Altos are making any progress on the underlying science. Morgan Levine came out with a useful algorithm, but we need to move on from these things. ---
**Author:** ![desertshores](https://www.rapamycin.news/user_avatar/www.rapamycin.news/desertshores/32/17120_2.png) [@desertshores](https://www.rapamycin.news/u/desertshores)\ **Post date:** [August 17, 2026, 9:15pm UTC](https://www.rapamycin.news/t/joanne-mannick-joining-altos-labs/20949/10 "2026-08-17T21:15:54Z")
America is the home of genius start up tech companies. Two “geniuses” meet over a cocktail or dinner. They always think that they are smarter than the other geniuses that made a successful startup and became millionaires after selling out to big pharma. Alas, the vast majority are doomed to failure. Even as I type this, still another “New Innovative Tech Company” is being formed. Often from the dregs of other failed companies.