# Ergothioneine - An Anti-aging compound to watch **URL:** \ **Category:** General\ **Created:** [December 1, 2021, 9:50pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339 "2021-12-01T21:50:21Z")\ **Posts on this page:** 20\ **Page:** 1
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [December 1, 2021, 9:50pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/1 "2021-12-01T21:50:21Z")
I eat a lot more shiitake and oyster mushrooms after I learned about this compound. Anyone else here tracking it and adjusting their diet to accommodate it? > Ergothioneine is a sulfur-containing amino acid that acts as an antioxidant and has a unique role in the protection of mitochondria from oxidation. It is only obtained from dietary sources with mushrooms being a top source. (2) Depending on the variety, one serving of [mushrooms](https://www.mushroomcouncil.com/wp-content/uploads/2017/12/Mushroom-Nutrition-At-A-Glance.pdf) can contain 2.4 to 4.9mg of ergothioneine. Mushrooms that contain the highest amounts of ergothioneine include King oyster, maitake, oyster, and shiitake [varieties](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056650/#!po=31.2500). It can also be found in black beans, red beans and oat bran. > [Source](https://nutrition.org/magnificent-mushrooms/) Related reading and video: > **[Mushrooms are 'the richest source' antioxidants that fight age-related diseases](https://www.zmescience.com/medicine/nutrition-medicine/mushrooms-antioxidants-rich/)** > > For once, something that tastes good is actually healthy for you. [![](https://img.youtube.com/vi/UEgBxCk9fb0/maxresdefault.jpg "Ergothioneine: A 'Longevity Vitamin' With Potential Benefits For Age-Related Outcomes?") ](https://www.youtube.com/watch?v=UEgBxCk9fb0) ---
**Author:** ![Agetron](https://www.rapamycin.news/user_avatar/www.rapamycin.news/agetron/32/40772_2.png) [@Agetron](https://www.rapamycin.news/u/Agetron)\ **Post date:** [February 12, 2023, 6:44am UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/2 "2023-02-12T06:44:04Z")
Just for @Bicep Life Extension magazine had an update on mushrooms too! ![Life Extension musg](https://www.rapamycin.news/uploads/default/original/2X/d/d6f85c6b96fe3be6609033f1676f6a25309e3b02.jpeg) ![Life Extension musg 1](https://www.rapamycin.news/uploads/default/original/2X/4/48cbbcbaa2f5265ededaa3650c7dce2c1ef00b92.jpeg) ![Life Extension musg 2](https://www.rapamycin.news/uploads/default/original/2X/f/f3abe4e499c16d7b325d040ce595edc81d8f1255.jpeg) ![Life Extension musg 3](https://www.rapamycin.news/uploads/default/original/2X/4/453fecaaca791bc594dab04827e2b896d1014a5c.jpeg) ---
**Author:** ![Agetron](https://www.rapamycin.news/user_avatar/www.rapamycin.news/agetron/32/40772_2.png) [@Agetron](https://www.rapamycin.news/u/Agetron)\ **Post date:** [February 12, 2023, 6:58am UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/3 "2023-02-12T06:58:39Z")
I guess it is time to add more mushrooms to my diet - I already like them! Bicep - do you have a friend special on those tasty fungi?!? ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [February 12, 2023, 8:48am UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/4 "2023-02-12T08:48:44Z")
I have been experimenting with allicin which is thought of as an HS donor available for creating mitochondria. (I think in the image this is misnamed as Alliin) I don’t know whether this has a separate effect from a sulphur containing amino acid as I don’t know that area of metabolism that much. At the moment I am getting some tingling that I wish to isolate out the cause of and it could be allicin, or it could be the form of B6 that I am taking (B6 has this odd self inhibition thing that means that taking too much causes the same problems as not having enough - however, I have been taking the active form for about 5 months). Hence I have dropped allicin temporarily. ---
**Author:** ![Joseph](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/j/dc4da7/32.png) [@Joseph](https://www.rapamycin.news/u/Joseph)\ **Post date:** [February 12, 2023, 11:25am UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/5 "2023-02-12T11:25:16Z")
FWIW… “Allicin is one of the main active compounds derived from garlic.” From; [Allicin: Uses, Benefits, Side Effects, Dosage, Precautions](https://www.verywellhealth.com/the-benefits-of-allicin-88606) ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [February 12, 2023, 12:15pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/6 "2023-02-12T12:15:31Z")
I am trying this: > **[ALLICINMAX® | Allimax International Limited](https://www.allicin.co.uk/section/12/1/allicinmax__)** > > Information about allicin, buy allicin products and view comparison of AllicinMax against other garlic products At the moment I have narrowed down my search for the tingle source to one of four supplements. I will probably revert to taking allicin once I have resolved this issue although as allicin can also cause tingling I will see if it is also causing tingling. ---
**Author:** ![Joseph](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/j/dc4da7/32.png) [@Joseph](https://www.rapamycin.news/u/Joseph)\ **Post date:** [February 12, 2023, 12:32pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/7 "2023-02-12T12:32:14Z")
A collection of published papers on ergothioneine see; > **[ergothioneine - Search Results - PubMed](https://pubmed.ncbi.nlm.nih.gov/?term=ergothioneine)** > > ergothioneine - Search Results - PubMed ---
**Author:** ![JuanDaw](https://www.rapamycin.news/user_avatar/www.rapamycin.news/juandaw/32/5311_2.png) [@JuanDaw](https://www.rapamycin.news/u/JuanDaw)\ **Post date:** [February 12, 2023, 1:42pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/8 "2023-02-12T13:42:38Z")
I buy oyster mushrooms (pleurotus ostreatus, not eryngii), and dehydrate them. Then I run the dried mushrooms through a coffee grinder. I take three grams in bone broth, or mix them into my food, if I am taking chili, or some stew type food (goulash, for example). I mix the three grams into my portion, not the cooking pot. Am looking for the link; ostreatus has more ERG than eryngii. The highest ERG among oyster mushrooms is yellow oyster. ---
**Author:** ![Bicep](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/b/13edae/32.png) [@Bicep](https://www.rapamycin.news/u/Bicep)\ **Post date:** [February 12, 2023, 2:38pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/9 "2023-02-12T14:38:50Z")
I saw that and bought a bag of plugs for the golden oyster, used cottonwood logs. Mycelium grew, but no fruit. This is a tropical mushroom, so freezing kills and I’m screwed. The wine cap is a mushroom that grows well here naturally, I buy a trailer of cottonwood chips, add the spawn and we get blooms all summer, then the next year too. ---
**Author:** ![Bicep](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/b/13edae/32.png) [@Bicep](https://www.rapamycin.news/u/Bicep)\ **Post date:** [February 12, 2023, 2:45pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/10 "2023-02-12T14:45:14Z")
Pyridoxal 5 phosphate should not make your fingers tingle no matter how much you take. Manufacturing cheaply makes vitamers with the other forms that cause the tingle. This is my understanding. ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [February 12, 2023, 2:56pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/11 "2023-02-12T14:56:09Z")
I think you are right and having done a certain amount of trial and error my current hypothesis is NMN is the cause. However, the tingle is a fact. I was previously taking B6 and that did cause a tingle which is why I shifted to the active form. As it stands I have stopped the active B6 and stopped allicin. ---
**Author:** ![John\_Hemming](https://www.rapamycin.news/user_avatar/www.rapamycin.news/john_hemming/32/6542_2.png) [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\ **Post date:** [October 16, 2023, 12:12pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/12 "2023-10-16T12:12:12Z")
Another video on ergothioneine [![](https://img.youtube.com/vi/G3ziW02h0aE/maxresdefault.jpg "Vitamin L: The Longevity Vitamin") ](https://www.youtube.com/watch?v=G3ziW02h0aE) ---
**Author:** ![JuanDaw](https://www.rapamycin.news/user_avatar/www.rapamycin.news/juandaw/32/5311_2.png) [@JuanDaw](https://www.rapamycin.news/u/JuanDaw)\ **Post date:** [October 16, 2023, 12:57pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/13 "2023-10-16T12:57:26Z")
My mistake. Pleurotus eryngii (king oyster) has almost three times the ERG content of pleurotus ostreatus. Yellow oyster is still tops. [https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/ergothioneine](https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/ergothioneine) _ **Mushroom fruiting body** _ a (Ey et al., 2007; Bao et al., 2010) _Flammulina populicola_ 48.00 _Flammulina velutipes_ 298.00 _Grifola frondosa_ 30.00 _Grifola frondosa_ (white) 8.00 _Hypsizygus tessellates_ 6.00 _Lentinula edodes_ **284.00** Shiitake _Pholiota nameko_ 2.00 _Pleurotus cornucopiae_ **2082.00** _Pleurotus eryngii_ **317.00** _Boletus edulis_ **528.14** Porcini _Pleurotus ostreatus_ **118.91** _Agaricus bisporus_ (brown) 0.93 _Agaricus bisporus_ (white) 0.46 _Cantharellus cibarius_ 0.06 ---
**Author:** ![Bicep](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/b/13edae/32.png) [@Bicep](https://www.rapamycin.news/u/Bicep)\ **Post date:** [October 16, 2023, 1:19pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/14 "2023-10-16T13:19:18Z")
That’s what I always thought too. According to the table you have here the winner is something called branched oyster or popcorn oyster. Thanks Juan. ---
**Author:** ![Danlalane](https://www.rapamycin.news/user_avatar/www.rapamycin.news/danlalane/32/1615_2.png) [@Danlalane](https://www.rapamycin.news/u/Danlalane)\ **Post date:** [October 16, 2023, 1:38pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/15 "2023-10-16T13:38:26Z")
Bryan Johnson’s BP super veggie recipe has 50g of Shiitake or Maitake, so been doing that daily. Probably no coincidence this is on the ingredients list. ---
**Author:** ![A\_User](https://www.rapamycin.news/user_avatar/www.rapamycin.news/a_user/32/40991_2.png) [@A\_User](https://www.rapamycin.news/u/A_User)\ **Post date:** [October 16, 2023, 2:11pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/16 "2023-10-16T14:11:59Z")
> [@JuanDaw](#): > > _Pleurotus cornucopiae_ **2082.00** Quite an appropriate name for something so abundant in ERG content. ![image](https://www.rapamycin.news/uploads/default/original/2X/d/de473dad5a667364f1ec72d7b3322013f75ac10b.png) ---
**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Post date:** [March 14, 2024, 4:17pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/17 "2024-03-14T16:17:42Z")
[![](https://i.ytimg.com/vi/TlPtdBnb0Hk/hqdefault.jpg "Ergothioneine Extends Lifespan In Worms, Flies, And Mice: What About In People?") ](https://www.youtube.com/watch?v=TlPtdBnb0Hk) and recent research information and research: [Inexpensive and natural source of glutathione and ergothioneine - #4 by RapAdmin](https://www.rapamycin.news/t/inexpensive-and-natural-source-of-glutathione-and-ergothioneine/8168/4) ---
**Author:** ![Bicep](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/b/13edae/32.png) [@Bicep](https://www.rapamycin.news/u/Bicep)\ **Post date:** [March 14, 2024, 4:25pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/18 "2024-03-14T16:25:50Z")
Kind of depressing really. He says it counts on the microbiome too. So I could be swallowing it like crazy and still not have a great amount in my bloodstream. Oh well, the spawn is here, the logs are ready and it’s raining today. I may wait another week because the ground is frozen most mornings and I don’t know how sensitive this stuff is. Also we’ve been really busy knifing anhydrous ammonia and starter so I have not had time anyway. ---
**Author:** ![JuanDaw](https://www.rapamycin.news/user_avatar/www.rapamycin.news/juandaw/32/5311_2.png) [@JuanDaw](https://www.rapamycin.news/u/JuanDaw)\ **Post date:** [March 14, 2024, 7:55pm UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/19 "2024-03-14T19:55:47Z")
Minute 4:01. To the left, the highest are Ergothioneine and beta carotene. Highest food sources for beta carotene are below: | Food | Beta-carotene content (in micrograms/mcg) per cup | | --- | --- | | Sweet potato (baked) | 23,018 mcg | | Carrots | 10,605 mcg | | Butternut squash (cooked) | 9,369 mcg | | Cantaloupe | 3,575 mcg | | Romaine lettuce | 2,456 mcg | | Red peppers | 2,420 mcg | | Spinach | 1,688 mcg | | Apricots | 1,696 mcg | | Broccoli (cooked) | 1,449 mcg | | Pea pods (cooked) | 1,216 mcg | | Mango (fresh) | 1,056 mcg | > **[Beta-Carotene: Where To Find It and Why You Need It](https://health.clevelandclinic.org/beta-carotene)** > > When you hear about beta-carotene, your mind might jump straight to carrots and eye health. But there’s more to this beneficial nutrient than that. Been tanking up on bell peppers. But might try the recipe below, this weekend, with glycine and xylitol. > **[Sweet Potato Pie](https://www.allrecipes.com/recipe/12142/sweet-potato-pie-i/)** > > This homemade sweet potato pie is a Southern recipe that's easy to make with boiled sweet potatoes. Try it, it may just be the best you've ever tasted! ---
**Author:** ![Bicep](https://www.rapamycin.news/letter_avatar_proxy/v4/letter/b/13edae/32.png) [@Bicep](https://www.rapamycin.news/u/Bicep)\ **Post date:** [March 15, 2024, 12:33am UTC](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339/20 "2024-03-15T00:33:17Z")
But Methionine reduces your HR, so it’s good for you. And Creatine and Trigonelline are on the right side, so they increase the HR. What gives here? Am I reading this wrong? [Next page](https://www.rapamycin.news/t/ergothioneine-an-anti-aging-compound-to-watch/339.md?page=2)