# BioAge Results for Phase 1b Clinical Trial on Anti Muscle-Aging Drug

**URL:** <https://www.rapamycin.news/t/bioage-results-for-phase-1b-clinical-trial-on-anti-muscle-aging-drug/5110>\
**Category:** General\
**Created:** [January 18, 2023, 11:59pm UTC](https://www.rapamycin.news/t/bioage-results-for-phase-1b-clinical-trial-on-anti-muscle-aging-drug/5110 "2023-01-18T23:59:53Z")\
**Posts on this page:** 1\
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**Author:** ![RapAdmin](https://www.rapamycin.news/user_avatar/www.rapamycin.news/rapadmin/32/377_2.png) [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Post date:** [January 19, 2023, 4:51pm UTC](https://www.rapamycin.news/t/bioage-results-for-phase-1b-clinical-trial-on-anti-muscle-aging-drug/5110/15 "2023-01-19T16:51:24Z")

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I’ve been searching a big on Apelin to learn more. Here is one quote from the book “[Defying Aging](https://www.amazon.com/Defy-Aging-Beginners-Science-Longer/dp/1538155141)”

> “Another important myokine is called apelin. Of course, its levels decline with age but are boosted by exercise. Its effects read like a fountain of youth: stimulating production of new mitochondria, facilitating protein synthesis, and helping muscle stem cells to function.14  
> Our skeletal muscles suck up a large proportion of the sugar circulating in the blood. As we lose muscle, blood sugar levels can rise contributing to an age-related risk for type 2 diabetes. Conversely, exercise stabilizes blood sugar levels.1”

From the sounds of it, it will be competitive with drugs being developed that target Irisin: [Irisin Ameliorates Age-associated Sarcopenia and Metabolic Dysfunction](https://www.rapamycin.news/t/irisin-ameliorates-age-associated-sarcopenia-and-metabolic-dysfunction/4453)

## Effect of endurance training on skeletal muscle myokine expression in obese men: identification of apelin as a novel myokine

[Apelin\_ijo.2013.158.pdf](https://www.rapamycin.news/uploads/short-url/y1WNEAu1powP9RqXXZo2Xp7yJ4c.pdf) (1.2 MB)

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