# Latest

**URL:** https://www.rapamycin.news/latest.md?page=4

[Latest](https://www.rapamycin.news/latest.md) · [Categories](https://www.rapamycin.news/categories.md) · [Tags](https://www.rapamycin.news/tags.md)

**Page:** 5

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## [Cutting Back on Sweets and Sugary Drinks May Help Protect the Aging Brain](https://www.rapamycin.news/t/cutting-back-on-sweets-and-sugary-drinks-may-help-protect-the-aging-brain/27296)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 31, 2026, 4:36am UTC](https://www.rapamycin.news/t/cutting-back-on-sweets-and-sugary-drinks-may-help-protect-the-aging-brain/27296 "2026-10-31T04:36:43Z")

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Using UK Biobank data from about 182,000 adults, researchers in China and Hong Kong grouped people by their food preferences into three profiles: health-aligned, broad-preference and sweet-tooth. The sweet-tooth group, who rated most foods low except sweets and sugary drinks, had a 79% higher hazard of dementia than the health-aligned group over a median of 13.8 years. Their hazard of Alzheimer…

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## [Exercise May Offset the Aging Cost of Sitting and Poor Sleep, a French Study Hints](https://www.rapamycin.news/t/exercise-may-offset-the-aging-cost-of-sitting-and-poor-sleep-a-french-study-hints/27293)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 31, 2026, 4:17am UTC](https://www.rapamycin.news/t/exercise-may-offset-the-aging-cost-of-sitting-and-poor-sleep-a-french-study-hints/27293 "2026-10-31T04:17:33Z")

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Researchers in Toulouse, France, examined how physical activity, sitting time and sleep quality relate, alone and in combination, to five biological aging clocks in 890 adults aged 20 to 102. The clocks were PhenoAge, GrimAge, DunedinPACE, the inflammatory clock iAge, and an intrinsic capacity clock. Activity, sitting and sleep were self-reported by questionnaire. Taken one at a time, the three…

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## [Fresh Sauerkraut Hints at Lower Inflammation, but More Microbes May Be Needed](https://www.rapamycin.news/t/fresh-sauerkraut-hints-at-lower-inflammation-but-more-microbes-may-be-needed/27290)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 31, 2026, 4:04am UTC](https://www.rapamycin.news/t/fresh-sauerkraut-hints-at-lower-inflammation-but-more-microbes-may-be-needed/27290 "2026-10-31T04:04:24Z")

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Researchers at the University of Freiburg in Germany asked whether eating sauerkraut every day improves gut barrier function, inflammation, blood sugar control or blood pressure in healthy adults. In a randomized crossover trial, 87 participants ate 100 grams a day of fresh, live-culture sauerkraut for four weeks and pasteurized sauerkraut for another four weeks. Each phase was preceded by a fo…

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## [Cystatin-C some thoughts and some references (blog post 17/8/26)](https://www.rapamycin.news/t/cystatin-c-some-thoughts-and-some-references-blog-post-17-8-26/26142)

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**Author:** [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\
**Replies:** 11\
**Last updated:** [October 31, 2026, 1:51am UTC](https://www.rapamycin.news/t/cystatin-c-some-thoughts-and-some-references-blog-post-17-8-26/26142 "2026-10-31T01:51:19Z")

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Cystatin-C has interested me for some time. It is used as a marker of Kidney function and in theory is a better marker than Creatinine. Creatinine has its problems, but it appears so does Cystatin-C. What I found interesting about Cystatin-C is that it is also a signalling molecule whilst Creatinine is a metabolic by product. Creatinine is produced mainly inside skeletal muscle by the spontaneo…

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## [What is the Rapamycin Dose / Dosage for Anti-Aging or Longevity?](https://www.rapamycin.news/t/what-is-the-rapamycin-dose-dosage-for-anti-aging-or-longevity/102)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 569\
**Last updated:** [October 30, 2026, 8:15pm UTC](https://www.rapamycin.news/t/what-is-the-rapamycin-dose-dosage-for-anti-aging-or-longevity/102 "2026-10-30T20:15:12Z")

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Rapamycin Dosing Level and Timing Here are the common dosing variables that I see people considering when they start dosing rapamycin for anti-aging (from an August, 2022 user poll here on our site): Note: Most users taking rapamycin for anti-aging, take between 3mg and 10mg per week, on a once-weekly dosing schedule. Our forum software doesn’t accommodate conditional branching in these s…

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## [Wild Blueberries: The "Elicited" Super-Polyphenol for Vascular Aging?](https://www.rapamycin.news/t/wild-blueberries-the-elicited-super-polyphenol-for-vascular-aging/23503)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 46\
**Last updated:** [October 30, 2026, 7:49pm UTC](https://www.rapamycin.news/t/wild-blueberries-the-elicited-super-polyphenol-for-vascular-aging/23503 "2026-10-30T19:49:47Z")

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This comprehensive review argues that wild blueberries (Vaccinium angustifolium) possess a superior cardiometabolic profile compared to their cultivated counterparts, driven by a phenomenon known as “elicitation.” Unlike cultivated highbush berries grown in optimized conditions, wild blueberries survive in harsh northern climates (Maine, Canada) with poor soil and extreme cold. These environmen…

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## [Higher Levels of hematocrit and hemoglobin - What is "High", What are the Risks? Testosterone Impact, etc](https://www.rapamycin.news/t/higher-levels-of-hematocrit-and-hemoglobin-what-is-high-what-are-the-risks-testosterone-impact-etc/27260)

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**Author:** [@LukeMV](https://www.rapamycin.news/u/LukeMV)\
**Replies:** 31\
**Last updated:** [October 30, 2026, 7:18pm UTC](https://www.rapamycin.news/t/higher-levels-of-hematocrit-and-hemoglobin-what-is-high-what-are-the-risks-testosterone-impact-etc/27260 "2026-10-30T19:18:11Z")

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I think one day, we will all realize that hematocrit and hemoglobin are markers and not causes of cardiovascular events. It could take ten more years before everyone comes to that consensus but it’s already beginning.

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## [Bypassing the Ice Bath: The Chemical Switch That Replicates Cold-Induced Longevity](https://www.rapamycin.news/t/bypassing-the-ice-bath-the-chemical-switch-that-replicates-cold-induced-longevity/27284)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 2\
**Last updated:** [October 30, 2026, 6:04pm UTC](https://www.rapamycin.news/t/bypassing-the-ice-bath-the-chemical-switch-that-replicates-cold-induced-longevity/27284 "2026-10-30T18:04:44Z")

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A study published in Nature reveals that the life-extending power of cold temperatures is governed by an active, multi-tissue metabolic communication network rather than passive thermodynamic slowing. Exposure to moderate cold triggers body wall muscle in Caenorhabditis elegans to upregulate the rate-limiting enzyme CAT-4, synthesizing dihydrobiopterin (BH2). Instead of acting locally, BH2 trav…

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## [New hair loss drug may reverse hair loss AND hair graying without touching DHT - ABS-201](https://www.rapamycin.news/t/new-hair-loss-drug-may-reverse-hair-loss-and-hair-graying-without-touching-dht-abs-201/26715)

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**Author:** [@AustraliaLongevity](https://www.rapamycin.news/u/AustraliaLongevity)\
**Replies:** 6\
**Last updated:** [October 30, 2026, 4:49pm UTC](https://www.rapamycin.news/t/new-hair-loss-drug-may-reverse-hair-loss-and-hair-graying-without-touching-dht-abs-201/26715 "2026-10-30T16:49:20Z")

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Executive Summary ABS-201 is a new experimental hair-loss drug targeting the prolactin receptor (PRLR) rather than DHT. The strongest interpretation is not that prolactin replaces DHT as the cause of androgenetic alopecia (AGA), but that PRLR signaling may be an additional upstream or parallel pathway affecting androgen signaling, hair cycling, and the follicular stem-cell niche. Th…

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## [Can Supplements Reverse Your Atherosclerosis? Testing 8 Options Against the Evidence - youtube Simon Hill](https://www.rapamycin.news/t/can-supplements-reverse-your-atherosclerosis-testing-8-options-against-the-evidence-youtube-simon-hill/25503)

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**Author:** [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\
**Replies:** 5\
**Last updated:** [October 30, 2026, 4:04pm UTC](https://www.rapamycin.news/t/can-supplements-reverse-your-atherosclerosis-testing-8-options-against-the-evidence-youtube-simon-hill/25503 "2026-10-30T16:04:56Z")

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chatGPT(5.5paid) The uploaded transcript is a YouTube episode about whether supplements can reverse atherosclerotic plaque, especially coronary plaque. I’ve cleaned out the adverts, repetitions, obvious transcription errors, and structured it below. The original transcript source is here: Summary The video argues that most supplements do not have strong evidence for reversing ather…

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## [Protect Your Aging Muscles by Logging Weekly Volume, Not Rest Times](https://www.rapamycin.news/t/protect-your-aging-muscles-by-logging-weekly-volume-not-rest-times/27222)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 30, 2026, 2:06pm UTC](https://www.rapamycin.news/t/protect-your-aging-muscles-by-logging-weekly-volume-not-rest-times/27222 "2026-10-30T14:06:56Z")

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In a 10-week trial, each volunteer’s legs were trained on a single-leg leg press at 80 percent of maximum. The legs used either 1-minute or 3-minute rests between sets, and the total workload was either matched or left unmatched. Rest length by itself had no measurable effect on muscle growth or strength. Legs that did more total work, whether through longer rests or through extra sets with sho…

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## [Tracking Famous People's Supplements and Stacks](https://www.rapamycin.news/t/tracking-famous-peoples-supplements-and-stacks/11133)

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**Author:** [@Jonas](https://www.rapamycin.news/u/Jonas)\
**Replies:** 17\
**Last updated:** [October 30, 2026, 1:52pm UTC](https://www.rapamycin.news/t/tracking-famous-peoples-supplements-and-stacks/11133 "2026-10-30T13:52:03Z")

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Rhonda Patrick: This is my current supplement stack: • Omega-3s (2g morning, 2g evening) • Vitamin D (5,000 IU/day) • Multivitamin (O.N.E. from Pure Encapsulations) • Magnesium glycinate (~125 mg, Pure Encapsulations) • Vitamin K2 (Life Extension) • CocoaVia • PQQ (20 mg/day, Life Extension) • Alpha-lipoic Acid (Pure Encapsulations) • Berberine (Thorne) • Lutein and Zeaxanthin (Pure Enca…

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## [Three Proteins in Your Blood Predict How Fast You're Aging. Here's What You Can Do About It](https://www.rapamycin.news/t/three-proteins-in-your-blood-predict-how-fast-youre-aging-heres-what-you-can-do-about-it/25259)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 25\
**Last updated:** [October 30, 2026, 1:37pm UTC](https://www.rapamycin.news/t/three-proteins-in-your-blood-predict-how-fast-youre-aging-heres-what-you-can-do-about-it/25259 "2026-10-30T13:37:46Z")

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Scientists have long suspected that aging, at its molecular core, follows a conserved script — that a mouse dying of old age and a human doing the same are, in some fundamental sense, running the same program. A landmark study published in Nature now provides the most comprehensive evidence yet that this is true, and offers a toolkit to read and score that program in real time from a blood samp…

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## [Celebrity Deaths](https://www.rapamycin.news/t/celebrity-deaths/20612)

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**Author:** [@Ambient](https://www.rapamycin.news/u/Ambient)\
**Replies:** 194\
**Last updated:** [October 30, 2026, 10:28am UTC](https://www.rapamycin.news/t/celebrity-deaths/20612 "2026-10-30T10:28:25Z")

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Post about whoever you want. Wanted to share a few people who died not too long ago who were in the longevity, supplement, and health industry. Durk Pearson. Aged 81. Cause of death: Not 100% sure but did read “He came down with a stomach infection that he couldn’t shake. It exploded into sepsis. By the time his friends medevacked him to the hospital in Reno it was too late.” October 26, 2024 …

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## [Total and beverage-specific alcohol use at mid-life and all-cause and cause-specific mortality: a prospective cohort study (paper 22nd July 2026)](https://www.rapamycin.news/t/total-and-beverage-specific-alcohol-use-at-mid-life-and-all-cause-and-cause-specific-mortality-a-prospective-cohort-study-paper-22nd-july-2026/27278)

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**Author:** [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 9:10am UTC](https://www.rapamycin.news/t/total-and-beverage-specific-alcohol-use-at-mid-life-and-all-cause-and-cause-specific-mortality-a-prospective-cohort-study-paper-22nd-july-2026/27278 "2026-10-30T09:10:11Z")

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I don’t think we have seen this one before even though it was published in July. I am currently tracking a period without alcohol, but I am intending to start drinking again probably in about a week’s time. It may be a little longer simply to have two more blood tests. My GGT started out in the normal range, but has reduced by about 20% during this. chatGPT(6max): This paper strengthens …

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## [Low-effort, low-calorie (or extremely healthy) foods and their estimated calorie counts/microplastic loads \[MasterList\]](https://www.rapamycin.news/t/low-effort-low-calorie-or-extremely-healthy-foods-and-their-estimated-calorie-counts-microplastic-loads-masterlist/20733)

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**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Replies:** 17\
**Last updated:** [October 30, 2026, 8:40am UTC](https://www.rapamycin.news/t/low-effort-low-calorie-or-extremely-healthy-foods-and-their-estimated-calorie-counts-microplastic-loads-masterlist/20733 "2026-10-30T08:40:08Z")

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PLEASE DO NOT PUT HIGH-CALORIE FOODS IN THIS THREAD, THERE IS ANOTHER THREAD FOR THAT NOW. \[this is more my list of foods I go for\], purely as a way to maximize vegetables/low-calorie foods as “convenience foods” eg SIMPLY ORGANIC PARSLEY (apigenin more concentrated, and WAY easier to eat than regular parsley, which is wrapped with plastic if you have it delivered to u) jovial tomatoes ======…

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## [Preserving Vitality: Kaempferol Re-establishes Peripheral Immune Defenses Without Thymus Regrowth](https://www.rapamycin.news/t/preserving-vitality-kaempferol-re-establishes-peripheral-immune-defenses-without-thymus-regrowth/27277)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 30, 2026, 5:15am UTC](https://www.rapamycin.news/t/preserving-vitality-kaempferol-re-establishes-peripheral-immune-defenses-without-thymus-regrowth/27277 "2026-10-30T05:15:23Z")

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A new preclinical study demonstrates that kaempferol, a common dietary flavonoid found in kale, spinach, and berries,effectively mitigates age-associated immune dysfunction and systemic inflammation in mice. Administering kaempferol to nineteen-month-old mice for eight weeks significantly improved physical performance, restoring grip strength and neuromuscular coordination while reducing depres…

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## [Fortifying the Gut Barrier: How Targeted Micronutrients Counter Inflammaging and Preserve Cellular Youth](https://www.rapamycin.news/t/fortifying-the-gut-barrier-how-targeted-micronutrients-counter-inflammaging-and-preserve-cellular-youth/27276)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 3:59am UTC](https://www.rapamycin.news/t/fortifying-the-gut-barrier-how-targeted-micronutrients-counter-inflammaging-and-preserve-cellular-youth/27276 "2026-10-30T03:59:28Z")

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As humans age, chronic low-grade systemic inflammation, termed inflammaging, drives functional decline,immunosenescence, and multimorbidity. This narrative review explores the mechanistic interplay between micronutrient status, gut microbiota dysbiosis, and immune competence. The authors synthesize biological pathways demonstrating that age-related shifts in gut flora increase intestinal permea…

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## [Gait, Grip, Memory and Mood: Four Measures That Predict How Well You Will Age](https://www.rapamycin.news/t/gait-grip-memory-and-mood-four-measures-that-predict-how-well-you-will-age/27275)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 3:46am UTC](https://www.rapamycin.news/t/gait-grip-memory-and-mood-four-measures-that-predict-how-well-you-will-age/27275 "2026-10-30T03:46:20Z")

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Researchers re-analyzed ASPREE, a large randomized trial of daily 100 mg aspirin versus placebo in 18,581 healthy adults aged 65 and older from Australia and the United States. They built an “intrinsic capacity” score from four domains measured each year: cognition, walking speed, grip strength and mood. They then checked the score against frailty, epigenetic clocks and the trial’s main outcome…

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## [Train Your Visual Search: How Sharpening Spatial Focus Preserves Reading Speed into Your Eighties](https://www.rapamycin.news/t/train-your-visual-search-how-sharpening-spatial-focus-preserves-reading-speed-into-your-eighties/27274)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 30, 2026, 3:26am UTC](https://www.rapamycin.news/t/train-your-visual-search-how-sharpening-spatial-focus-preserves-reading-speed-into-your-eighties/27274 "2026-10-30T03:26:19Z")

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Italian researchers tested 120 neurologically healthy adults aged 60 to 88 on a large battery of reading, attention, vision and cognitive tasks to find out what drives slower reading with age. Using statistical mediation, they found that general cognitive speed matters most. The Symbol Digit Modalities Test, which combines processing speed, working memory and inhibition, accounted for roughly a…

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## [Silent Heart Disease Mirrors the Premature Aging of Your Immune System](https://www.rapamycin.news/t/silent-heart-disease-mirrors-the-premature-aging-of-your-immune-system/27273)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 3:03am UTC](https://www.rapamycin.news/t/silent-heart-disease-mirrors-the-premature-aging-of-your-immune-system/27273 "2026-10-30T03:03:04Z")

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Coronary artery disease often progresses silently for years before causing symptoms. A cross-sectional clinical study of 967 middle-aged Swedish adults from the SCAPIS cohort investigated whether shifts in adaptive and innate immunity relate to hidden plaque buildup. Using multi-color flow cytometry on fresh whole blood and coronary computed tomography angiography, researchers identified an imm…

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## [Why Starting Aerobic Training Early Protects Against Middle-Age Muscle Loss](https://www.rapamycin.news/t/why-starting-aerobic-training-early-protects-against-middle-age-muscle-loss/27272)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 2:55am UTC](https://www.rapamycin.news/t/why-starting-aerobic-training-early-protects-against-middle-age-muscle-loss/27272 "2026-10-30T02:55:00Z")

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Sarcopenia is typically diagnosed late in life, yet its cellular foundations develop decades before clinical symptoms emerge. This investigation examined gastrocnemius muscle remodeling in male Wistar rats between young adulthood (8 months) and middle age (14 months), corresponding roughly to 22 and 35 human years. The authors evaluated whether lifelong moderate aerobic treadmill running mitiga…

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## [Eating for Cognitive Reserve: Fresh Foods Slash Odds of Late-Life Dementia](https://www.rapamycin.news/t/eating-for-cognitive-reserve-fresh-foods-slash-odds-of-late-life-dementia/27271)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 2:27am UTC](https://www.rapamycin.news/t/eating-for-cognitive-reserve-fresh-foods-slash-odds-of-late-life-dementia/27271 "2026-10-30T02:27:56Z")

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A cross-sectional investigation of 1,017 community-dwelling older adults from the Birjand Longitudinal Aging Study demonstrated that individuals consuming the highest amounts of unprocessed or minimally processed foods experienced a 48 percent reduction in the odds of major neurocognitive disorder compared to the lowest consumers. While contemporary public health messaging frequently identifies…

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## [Why Empagliflozin’s Cardiovascular Benefit May Start in Your White Blood Cells](https://www.rapamycin.news/t/why-empagliflozin-s-cardiovascular-benefit-may-start-in-your-white-blood-cells/27269)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 1:49am UTC](https://www.rapamycin.news/t/why-empagliflozin-s-cardiovascular-benefit-may-start-in-your-white-blood-cells/27269 "2026-10-30T01:49:30Z")

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Sixteen women who were obese and had blood sugar levels on the edge of diabetes took empagliflozin, a common diabetes drug, every day for twelve weeks. Doctors drew their blood three times: before they started, after two weeks, and at the end. They were looking for a particular troublemaker in the blood. Platelets are the tiny cells that help blood clot, and when they get activated they sometim…

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## [Rapamycin Prevents Thyroid Hormone-Induced Cardiac Hypertrophy](https://www.rapamycin.news/t/rapamycin-prevents-thyroid-hormone-induced-cardiac-hypertrophy/20844)

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**Author:** [@Biohackerofthegods](https://www.rapamycin.news/u/Biohackerofthegods)\
**Replies:** 1\
**Last updated:** [October 30, 2026, 12:55am UTC](https://www.rapamycin.news/t/rapamycin-prevents-thyroid-hormone-induced-cardiac-hypertrophy/20844 "2026-10-30T00:55:36Z")

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Thyroid hormones (THs) have many effects on the cardiovascular system including cardiac hypertrophy. Although THs induce cardiac hypertrophy, the mechanism through which they exert this effect is unknown. We previously found that THs activate signaling related to increased protein synthesis \[mammalian target of rapamycin (mTOR) and p70 S6 kinase\] in the heart. It is unknown whether this activation…

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## [Five Sleep Habits Linked to a 24% Lower Risk of Thyroid Disease](https://www.rapamycin.news/t/five-sleep-habits-linked-to-a-24-lower-risk-of-thyroid-disease/27268)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 12:53am UTC](https://www.rapamycin.news/t/five-sleep-habits-linked-to-a-24-lower-risk-of-thyroid-disease/27268 "2026-10-30T00:53:32Z")

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Using data from 499,084 UK Biobank participants aged 37 to 73, researchers at Harbin Medical University built a 0-to-5 healthy sleep score from five self-reported habits: 7 to 8 hours of sleep, morning chronotype, no frequent insomnia, no snoring and no frequent daytime sleepiness. Over roughly 12 years of follow-up, about 15,000 people were diagnosed with thyroid disease. Compared with those s…

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## [Is There Anything BPC-157 Can’t Cure? (Atlantic)](https://www.rapamycin.news/t/is-there-anything-bpc-157-can-t-cure-atlantic/27249)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 30, 2026, 12:52am UTC](https://www.rapamycin.news/t/is-there-anything-bpc-157-can-t-cure-atlantic/27249 "2026-10-30T00:52:40Z")

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The wellness industry loves a secret cure. I encountered dozens of them at Dave Asprey’s Beyond Biohacking Conference, held in May on several floors of a hotel in downtown Austin. There were supplements galore, of course: algae tablets for detoxification, ketones for concentration, nitric oxide for circulation. One company claimed that its capsules contained quantum energy. I saw people hooked to…

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## [Your 20s Waistline May Shape Your Cancer Risk at 40](https://www.rapamycin.news/t/your-20s-waistline-may-shape-your-cancer-risk-at-40/27266)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 30, 2026, 12:29am UTC](https://www.rapamycin.news/t/your-20s-waistline-may-shape-your-cancer-risk-at-40/27266 "2026-10-30T00:29:51Z")

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Using South Korea’s national health insurance database, researchers followed 6,313,338 adults aged 20 to 39 who had a health screening between 2009 and 2012, for an average of 11.2 years. Height, weight and waist were measured, not self-reported. A total of 151,893 cancers were diagnosed. Ten-year cancer incidence rose stepwise from 1.84% at normal weight to 2.24% in class I obesity and 2.62% i…

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## [Cardio improves how your arteries work, and the fitter and leaner you get, the bigger the gain](https://www.rapamycin.news/t/cardio-improves-how-your-arteries-work-and-the-fitter-and-leaner-you-get-the-bigger-the-gain/27261)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 1\
**Last updated:** [October 29, 2026, 11:40am UTC](https://www.rapamycin.news/t/cardio-improves-how-your-arteries-work-and-the-fitter-and-leaner-you-get-the-bigger-the-gain/27261 "2026-10-29T11:40:22Z")

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Researchers from the University of Ljubljana in Slovenia pooled 72 randomized controlled trials, with 3,357 participants, that compared aerobic training against no exercise. They focused on brachial-artery flow-mediated dilation (FMD), an ultrasound test of how well an artery widens in response to increased blood flow. Programs lasting 4 to 26 weeks raised FMD by 2.35 percentage points on avera…

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## [Toxic By Design: How Water Turns 'Inert' Microplastics Into Spontaneous Free Radical Generators](https://www.rapamycin.news/t/toxic-by-design-how-water-turns-inert-microplastics-into-spontaneous-free-radical-generators/27081)

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**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 8\
**Last updated:** [October 29, 2026, 11:38pm UTC](https://www.rapamycin.news/t/toxic-by-design-how-water-turns-inert-microplastics-into-spontaneous-free-radical-generators/27081 "2026-10-29T23:38:50Z")

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Commodity plastics have universally been considered chemically inert. This study reveals a profound paradigm shift: when fragmented into microplastics and suspended in pure water, common materials like polyethylene, polypropylene, and polystyrene spontaneously and continuously generate highly reactive hydroxyl radicals. This physicochemical activity is driven purely by water-hydrophobe interact…

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