# Latest

**URL:** https://www.rapamycin.news/latest.md?page=1

[Latest](https://www.rapamycin.news/latest.md) · [Categories](https://www.rapamycin.news/categories.md) · [Tags](https://www.rapamycin.news/tags.md)

**Page:** 2

---

## [E/A ratio on echocardiography? What are ways to improve it?](https://www.rapamycin.news/t/e-a-ratio-on-echocardiography-what-are-ways-to-improve-it/27342)

<div class="topic-metadata">

**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Replies:** 7\
**Last updated:** [November 5, 2026, 6:47pm UTC](https://www.rapamycin.news/t/e-a-ratio-on-echocardiography-what-are-ways-to-improve-it/27342 "2026-11-05T18:47:52Z")

</div>

And what values have you gotten?

---

## [Just a little humor](https://www.rapamycin.news/t/just-a-little-humor/12176)

<div class="topic-metadata">

**Author:** [@ng0rge](https://www.rapamycin.news/u/ng0rge)\
**Replies:** 485\
**Last updated:** [November 4, 2026, 11:14pm UTC](https://www.rapamycin.news/t/just-a-little-humor/12176 "2026-11-04T23:14:12Z")

</div>

I haven’t been on this forum all that long but I’m a quick learner and just wanted to pass on some of my observations and tips for new users. The quickest way to make friends here is: 1) Attack David Sinclair. 2) Never refer to Peter Attia as “that muscle bound geek” but it is OK to disagree with his obsession with protein intake. 3) Post about Bryan Johnson’s…“johnson” (The underground press …

---

## [Wall Street Journal Says No More Cheap Overseas Prescriptions Shipped to USA?](https://www.rapamycin.news/t/wall-street-journal-says-no-more-cheap-overseas-prescriptions-shipped-to-usa/26737)

<div class="topic-metadata">

**Author:** [@lillycat](https://www.rapamycin.news/u/lillycat)\
**Replies:** 270\
**Last updated:** [November 4, 2026, 8:39pm UTC](https://www.rapamycin.news/t/wall-street-journal-says-no-more-cheap-overseas-prescriptions-shipped-to-usa/26737 "2026-11-04T20:39:06Z")

</div>

Ola Friends! YIKES! WSJ had an article yesterday saying that new regulations are being enacted starting October 22, 2026 that will shut down USA citizens ability to order prescription drugs from Canada, and other overseas sources. Did anyone see this? Will this shut down our rapamycin sources from places such as India? I’m worried!

---

## [Losing Visceral Fat May Matter More Than Gaining Lean Mass for Blood Sugar](https://www.rapamycin.news/t/losing-visceral-fat-may-matter-more-than-gaining-lean-mass-for-blood-sugar/27356)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [November 4, 2026, 7:15pm UTC](https://www.rapamycin.news/t/losing-visceral-fat-may-matter-more-than-gaining-lean-mass-for-blood-sugar/27356 "2026-11-04T19:15:13Z")

</div>

Researchers at Pennington Biomedical Research Center analyzed 59,269 UK Biobank participants with both DXA and MRI body composition scans. They asked why higher fat-free mass, usually considered metabolically protective, keeps turning up in large studies as a risk factor for insulin resistance. Absolute fat-free mass and fat-free mass scaled to height were linked to more metabolic syndrome and …

---

## [Canagliflozin - Another Top Longevity Drug](https://www.rapamycin.news/t/canagliflozin-another-top-longevity-drug/91)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 2157\
**Last updated:** [November 4, 2026, 6:04pm UTC](https://www.rapamycin.news/t/canagliflozin-another-top-longevity-drug/91 "2026-11-04T18:04:51Z")

</div>

Canagliflozin: Significant Lifespan Extension Results in Male Mice Results of the National Institutes on Aging, ITP study Canagliflozin extends life span in genetically heterogeneous male but not female mice Increased median lifespan in the male mice by 14%, maximum extension of 9% But had no effect on the females Canagliflozin is in the class of drugs known as SGLT2 inhibitors. SGLT2 inhi…

---

## [Chat GPT and AI in Healthcare Thread](https://www.rapamycin.news/t/chat-gpt-and-ai-in-healthcare-thread/6383)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 323\
**Last updated:** [November 4, 2026, 6:03pm UTC](https://www.rapamycin.news/t/chat-gpt-and-ai-in-healthcare-thread/6383 "2026-11-04T18:03:41Z")

</div>

Since Chat GPT isn’t exactly longevity related, lets try keeping all related news and discussions on this in this one thread. I saw this recently: also, from the MIT Tech Review “Algorithm” newsletter: Health care I spoke with Nikhil Buduma and Mike Ng, the cofounders of Ambience Health, which is funded by OpenAI. The startup uses GPT-4 to generate medical documentation based on provider-pa…

---

## [Buy Rapamycin Online - List of Reliable Pharmacies](https://www.rapamycin.news/t/buy-rapamycin-online-list-of-reliable-pharmacies/437)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 2014\
**Last updated:** [November 4, 2026, 5:35pm UTC](https://www.rapamycin.news/t/buy-rapamycin-online-list-of-reliable-pharmacies/437 "2026-11-04T17:35:53Z")

</div>

Many people like to buy their rapamycin (sirolimus) online, to save money and simplify their purchase. Below is a list of vendors that users here say they have received shipments from without problems and without need for a prescription. Results may vary by country being shipped to, due to different importation rules and regulations. Generally, these are reliable pharmacies if you get a reliable …

---

## [Keeping Your VO2peak Above 26 Is Linked to Slower Biological Aging in Older Men](https://www.rapamycin.news/t/keeping-your-vo2peak-above-26-is-linked-to-slower-biological-aging-in-older-men/27355)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [November 4, 2026, 5:17pm UTC](https://www.rapamycin.news/t/keeping-your-vo2peak-above-26-is-linked-to-slower-biological-aging-in-older-men/27355 "2026-11-04T17:17:26Z")

</div>

Japanese researchers measured peak oxygen uptake with breath-by-breath gas analysis in 144 men aged 65 to 72 and compared it with DunedinPACE, a blood DNA methylation measure of how fast a person is biologically aging. Men with higher aerobic fitness tended to have a slightly slower pace of aging, and the link held after accounting for age, smoking, and drinking. Using a resampling-based classi…

---

## [ChefNMR2 (structural elucidation of chemicals, including rapamycin, from NMR spectra)](https://www.rapamycin.news/t/chefnmr2-structural-elucidation-of-chemicals-including-rapamycin-from-nmr-spectra/27352)

<div class="topic-metadata">

**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Replies:** 0\
**Last updated:** [November 4, 2026, 3:47pm UTC](https://www.rapamycin.news/t/chefnmr2-structural-elucidation-of-chemicals-including-rapamycin-from-nmr-spectra/27352 "2026-11-04T15:47:08Z")

</div>

---

## [A Heart Pill and a Vibrating Mattress May Clear Alzheimer’s Protein From The Brain](https://www.rapamycin.news/t/a-heart-pill-and-a-vibrating-mattress-may-clear-alzheimer-s-protein-from-the-brain/27345)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 2\
**Last updated:** [November 4, 2026, 5:30am UTC](https://www.rapamycin.news/t/a-heart-pill-and-a-vibrating-mattress-may-clear-alzheimer-s-protein-from-the-brain/27345 "2026-11-04T05:30:26Z")

</div>

Finnish researchers tested whether manipulating blood vessels could push proteins out of the human brain and into the bloodstream. Twenty-nine healthy adults aged 27 to 61 received sublingual nitroglycerin, a nitric oxide donor that relaxes arteries and lowers blood pressure, combined with 37 minutes of patterned whole-body vibration designed to stimulate the mechanosensitive Piezo1 channel. Af…

---

## [Each Year Your Brain Looks Younger Is Worth About a Year of Memory](https://www.rapamycin.news/t/each-year-your-brain-looks-younger-is-worth-about-a-year-of-memory/27258)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [October 28, 2026, 9:41pm UTC](https://www.rapamycin.news/t/each-year-your-brain-looks-younger-is-worth-about-a-year-of-memory/27258 "2026-10-28T21:41:32Z")

</div>

Researchers from the University of South Carolina and the Icelandic Heart Association used structural MRI scans from 4,606 older Icelanders (average age 76) to estimate each person’s “brain age,” then compared it with their actual age. People whose brains looked older than their years scored lower on memory, processing speed and executive function tests, independent of age, sex and education. I…

---

## [Menaquinone-7 (MK-7): An interesting molecule to power up the mitochondria](https://www.rapamycin.news/t/menaquinone-7-mk-7-an-interesting-molecule-to-power-up-the-mitochondria/18438)

<div class="topic-metadata">

**Author:** [@John\_Hemming](https://www.rapamycin.news/u/John_Hemming)\
**Replies:** 106\
**Last updated:** [November 4, 2026, 2:35am UTC](https://www.rapamycin.news/t/menaquinone-7-mk-7-an-interesting-molecule-to-power-up-the-mitochondria/18438 "2026-11-04T02:35:55Z")

</div>

@adssx and I have been experimenting with Menaquinone-7 more recently. I am perhaps more enthused than he is. Menaquinone-7 is one of the types of Vitamin K2. These range from MK4 to MK13, but MK7 is one of the three types that can be bought as supplements (the other two are MK4 and MK9). What I find interesting about MK7 is that it can assist the electron transport chain and make mitochondri…

---

## [Predicting and Preventing Alzheimers & Dementia (and minimizing risk)](https://www.rapamycin.news/t/predicting-and-preventing-alzheimers-dementia-and-minimizing-risk/13060)

<div class="topic-metadata">

**Author:** [@Deborah\_Hall](https://www.rapamycin.news/u/Deborah_Hall)\
**Replies:** 1108\
**Last updated:** [November 3, 2026, 11:41pm UTC](https://www.rapamycin.news/t/predicting-and-preventing-alzheimers-dementia-and-minimizing-risk/13060 "2026-11-03T23:41:08Z")

</div>

Alzheimers is #1 in my priority of worries. At present, age 74, I have no issues or warning signs. But my mother, aunt and grandmother, all very long lived, have/had it. I am well and fit, but A1C has been 5.7-5.8 for many years with no progression. Taking Metformin. I just ordered some Rapamycin. Aware that if take it before there are amyloid placques, Rapa can be protective. But if taken…

---

## [Paperclip Datasets - Curate your own datasets from millions of papers in minutes](https://www.rapamycin.news/t/paperclip-datasets-curate-your-own-datasets-from-millions-of-papers-in-minutes/27344)

<div class="topic-metadata">

**Author:** [@AlexKChen](https://www.rapamycin.news/u/AlexKChen)\
**Replies:** 1\
**Last updated:** [November 3, 2026, 11:31pm UTC](https://www.rapamycin.news/t/paperclip-datasets-curate-your-own-datasets-from-millions-of-papers-in-minutes/27344 "2026-11-03T23:31:15Z")

</div>

Curate your own datasets from millions of papers in minutes. Just describe the dataset you want to build! James Zou on X: "Very excited to introduce Paperclip Datasets! Curate your own datasets from millions of papers in minutes. Just describe the dataset you want to build! As example, we release the largest dataset of 20k half-life human measurements curated from 2400+ drugs💊 🖇️ Try it: https:/…

---

## [Opinion about Finasteride and DHT](https://www.rapamycin.news/t/opinion-about-finasteride-and-dht/9234)

<div class="topic-metadata">

**Author:** [@Tom34](https://www.rapamycin.news/u/Tom34)\
**Replies:** 416\
**Last updated:** [November 3, 2026, 4:30pm UTC](https://www.rapamycin.news/t/opinion-about-finasteride-and-dht/9234 "2026-11-03T16:30:42Z")

</div>

Hi everyone. I would like to discuss here whats your opinion about finasteride or more generally about DHT. We already know finasteride is used both for hairloss and prostate. However its not what I want to discuss here. It was proven that balding people have a strong relationship with… cardiovascular disease. It was never proven however that male patern baldness is associated with high serum …

---

## [Reverse Gray Hair, Hair Repigmentation](https://www.rapamycin.news/t/reverse-gray-hair-hair-repigmentation/2765)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 699\
**Last updated:** [November 3, 2026, 4:27pm UTC](https://www.rapamycin.news/t/reverse-gray-hair-hair-repigmentation/2765 "2026-11-03T16:27:24Z")

</div>

Many people like the idea of reversing gray hair, and regaining their youthful hair color and thickness, or preventing gray hair entirely before it starts. The topical drug treatment program outlined below was developed by RiverTown Therapeutics and has some reasonable clinical data and photographs that demonstrate some significant results (scroll down to see images). So, I’ve pulled this post ou…

---

## [For insomnia, the medication that doesn't disrupt sleep architecture is trazodone](https://www.rapamycin.news/t/for-insomnia-the-medication-that-doesnt-disrupt-sleep-architecture-is-trazodone/25771)

<div class="topic-metadata">

**Author:** [@nikney](https://www.rapamycin.news/u/nikney)\
**Replies:** 8\
**Last updated:** [November 3, 2026, 2:37pm UTC](https://www.rapamycin.news/t/for-insomnia-the-medication-that-doesnt-disrupt-sleep-architecture-is-trazodone/25771 "2026-11-03T14:37:43Z")

</div>

What is your experience with trazodone for insomnia? As you know, trazodone has a half-life of 5-6 hours, so it doesn’t cause drowsiness the next day. It lowers cortisol through 5-HT2 receptor antagonistism and increases non-REM stages 3-4, which are deep sleep stages. It doesn’t suppress REM sleep. It has no anticholinergic effect, which makes it a good option for chronic use. Also, recent studie…

---

## [Inflammation Dropped to ZERO After 90 Days of Tirzepatide Microdosing (Full Doctor Lab Review)](https://www.rapamycin.news/t/inflammation-dropped-to-zero-after-90-days-of-tirzepatide-microdosing-full-doctor-lab-review/25784)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 34\
**Last updated:** [November 3, 2026, 2:27pm UTC](https://www.rapamycin.news/t/inflammation-dropped-to-zero-after-90-days-of-tirzepatide-microdosing-full-doctor-lab-review/25784 "2026-11-03T14:27:19Z")

</div>

I. Executive Summary This analysis evaluates the immunometabolic impact of sub-therapeutic, low-dose (“microdosed”) tirzepatide—a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist—on systemic inflammation, lipid architecture, and metabolic homeostasis in non-obese phenotypes. The core thesis posits that sub-therapeutic incret…

---

## [SUGGESTIONS? What Company or MDs can I Hire To Get Me to 120 Years of Age?](https://www.rapamycin.news/t/suggestions-what-company-or-mds-can-i-hire-to-get-me-to-120-years-of-age/26539)

<div class="topic-metadata">

**Author:** [@TBI-CHI](https://www.rapamycin.news/u/TBI-CHI)\
**Replies:** 106\
**Last updated:** [November 3, 2026, 2:09pm UTC](https://www.rapamycin.news/t/suggestions-what-company-or-mds-can-i-hire-to-get-me-to-120-years-of-age/26539 "2026-11-03T14:09:49Z")

</div>

I need to know which company or team can change my life and help me extend my healthspan and lifespan. Please name names. I may not have millions but whatever I have I’ll spend now. Born in 1960. I’ve not got outstanding health but I am stable and 66 now. I am a bit overweight but am trying to cut it down again. I used to be one heck of an athlete up until I was around 43. In 1995, I was 6%…

---

## [ARA290 (cibinetide) amelioration of frailty and preserved healthspan +Alzheimers prevention in mice](https://www.rapamycin.news/t/ara290-cibinetide-amelioration-of-frailty-and-preserved-healthspan-alzheimers-prevention-in-mice/15193)

<div class="topic-metadata">

**Author:** [@dankeen](https://www.rapamycin.news/u/dankeen)\
**Replies:** 7\
**Last updated:** [November 3, 2026, 9:43am UTC](https://www.rapamycin.news/t/ara290-cibinetide-amelioration-of-frailty-and-preserved-healthspan-alzheimers-prevention-in-mice/15193 "2026-11-03T09:43:10Z")

</div>

A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan - PMC. “Aging is associated with increased levels of reactive oxygen species and inflammation that disrupt proteostasis and mitochondrial function and leads to organism-wide frailty later in life. ARA290 (cibinetide), an 11-aa non-hema…

---

## [Purple Food, Clearer Mind? How Berry Pigments May Shield the Brain From a Junk Food Diet](https://www.rapamycin.news/t/purple-food-clearer-mind-how-berry-pigments-may-shield-the-brain-from-a-junk-food-diet/27324)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 13\
**Last updated:** [November 3, 2026, 6:30am UTC](https://www.rapamycin.news/t/purple-food-clearer-mind-how-berry-pigments-may-shield-the-brain-from-a-junk-food-diet/27324 "2026-11-03T06:30:48Z")

</div>

This review from the University of California, Davis, gathers preclinical, clinical and cell-culture evidence on whether anthocyanins, the red, purple and blue pigments in berries, purple vegetables and pigmented grains, can protect the brain from the damage linked to obesity and high-fat Western diets. The authors argue that the benefits begin in the gut. Very little intact anthocyanin is abso…

---

## [Can science make your dog live longer? Longevity craze comes to pets](https://www.rapamycin.news/t/can-science-make-your-dog-live-longer-longevity-craze-comes-to-pets/27336)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 0\
**Last updated:** [November 3, 2026, 3:59am UTC](https://www.rapamycin.news/t/can-science-make-your-dog-live-longer-longevity-craze-comes-to-pets/27336 "2026-11-03T03:59:46Z")

</div>

The emerging science — and industry — of animal longevity is attracting interest from companies and academics alike. Vera Gorbunova has attended many a longevity conference over her decades of studying ageing. But never one quite like this. Earlier this month, Gorbunova, a researcher at Rochester University in New York, joined scientists from industry and academia — and a fair few of their dogs…

---

## [Lifelong Aerobic Exercisers Have Nearly Double the Heart Rate Variability of Inactive Peers](https://www.rapamycin.news/t/lifelong-aerobic-exercisers-have-nearly-double-the-heart-rate-variability-of-inactive-peers/27299)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 10\
**Last updated:** [November 3, 2026, 3:04am UTC](https://www.rapamycin.news/t/lifelong-aerobic-exercisers-have-nearly-double-the-heart-rate-variability-of-inactive-peers/27299 "2026-11-03T03:04:48Z")

</div>

Researchers at Université Côte d’Azur in Nice, France, compared 19 healthy adults over 55 who had done structured aerobic exercise at least three times a week for 30 years with 20 healthy, lifelong inactive peers. They built a “vitality capacity” score from 12 measures proposed by a World Health Organization working group, grouped into three domains: immune and stress response, energy and metab…

---

## [Imeglimin. A new and novel drug thats better than Metformin](https://www.rapamycin.news/t/imeglimin-a-new-and-novel-drug-thats-better-than-metformin/23036)

<div class="topic-metadata">

**Author:** [@egorvj](https://www.rapamycin.news/u/egorvj)\
**Replies:** 169\
**Last updated:** [November 3, 2026, 2:48am UTC](https://www.rapamycin.news/t/imeglimin-a-new-and-novel-drug-thats-better-than-metformin/23036 "2026-11-03T02:48:42Z")

</div>

Has anyone knowledge about this drug? Its from Japan, I suppose. And it can be “a new better version” of metformin. Maybe someone knows any reviews from some smart guys like Johnson or Sinclair or Kaeberlein?

---

## [Simon Hill, MSc BSc, The Proof Podcast - Videos and Summaries](https://www.rapamycin.news/t/simon-hill-msc-bsc-the-proof-podcast-videos-and-summaries/26365)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 6\
**Last updated:** [November 3, 2026, 2:32am UTC](https://www.rapamycin.news/t/simon-hill-msc-bsc-the-proof-podcast-videos-and-summaries/26365 "2026-11-03T02:32:25Z")

</div>

How to switch your body from burning sugar to fat | Metabolic Masterclass | EP#429 I. Executive Summary Metabolic health represents the cellular capacity to efficiently oxidize substrates—fatty acids and glucose—within mitochondria to sustain bioenergetic homeostasis. Cardiometabolic diseases, including type 2 diabetes (T2D), metabolic dysfunction-associated steatotic liver disease (…

---

## [Life Expectancy in the USA and Around the world](https://www.rapamycin.news/t/life-expectancy-in-the-usa-and-around-the-world/2915)

<div class="topic-metadata">

**Author:** [@Agetron](https://www.rapamycin.news/u/Agetron)\
**Replies:** 587\
**Last updated:** [November 3, 2026, 1:36am UTC](https://www.rapamycin.news/t/life-expectancy-in-the-usa-and-around-the-world/2915 "2026-11-03T01:36:19Z")

</div>

“The longevity gap between men and women also grew by a couple of months in 2021. American women can now expect to live 79.1 years, almost six years longer than men, whose average life expectancy was 73.2 last year, according to the new data.” Overall, the sharpest two-year decline in nearly 100 years - from average of 79 years to 73 years – a 6.5 years drop. Link: https://www.nytimes.com/2022…

---

## [Great Interview With Dr. Karl Pfleger](https://www.rapamycin.news/t/great-interview-with-dr-karl-pfleger/27334)

<div class="topic-metadata">

**Author:** [@A\_User](https://www.rapamycin.news/u/A_User)\
**Replies:** 1\
**Last updated:** [November 3, 2026, 2:05am UTC](https://www.rapamycin.news/t/great-interview-with-dr-karl-pfleger/27334 "2026-11-03T02:05:26Z")

</div>

Discussed: early google thinking, multi disease targeting, intelligence research, aging as a target for doing good, ideal futures, disabilities from aging, revert to age 20-30, second careers, never have to retire, it’s achievable, need apollo program funding, LEV is sound, etc.

---

## [Peter Attia Podcasts - Transcripts / Analysis](https://www.rapamycin.news/t/peter-attia-podcasts-transcripts-analysis/22648)

<div class="topic-metadata">

**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\
**Replies:** 26\
**Last updated:** [November 2, 2026, 11:25pm UTC](https://www.rapamycin.news/t/peter-attia-podcasts-transcripts-analysis/22648 "2026-11-02T23:25:29Z")

</div>

The ketogenic diet, ketosis, and hyperbaric oxygen: weight loss, cognition, cancer, and more AI summary: Based on the transcript provided featuring Dom D’Agostino and Peter Attia, here is the summary and analysis. A. Executive Summary In this episode of The Drive, Peter Attia and Dr. Dom D’Agostino discuss the evolution of the ketogenic diet from a niche epilepsy treatment to a broa…

---

## [Sheekey and a take on rejuvenation](https://www.rapamycin.news/t/sheekey-and-a-take-on-rejuvenation/25866)

<div class="topic-metadata">

**Author:** [@Curious](https://www.rapamycin.news/u/Curious)\
**Replies:** 3\
**Last updated:** [November 2, 2026, 9:44pm UTC](https://www.rapamycin.news/t/sheekey-and-a-take-on-rejuvenation/25866 "2026-11-02T21:44:25Z")

</div>

She really dives into the science in only 9 min and 30 sec.

---

## [ELF Score as a Marker for Systemic Inflammation and Fibrosis](https://www.rapamycin.news/t/elf-score-as-a-marker-for-systemic-inflammation-and-fibrosis/27270)

<div class="topic-metadata">

**Author:** [@cronoslogical](https://www.rapamycin.news/u/cronoslogical)\
**Replies:** 6\
**Last updated:** [November 2, 2026, 9:42pm UTC](https://www.rapamycin.news/t/elf-score-as-a-marker-for-systemic-inflammation-and-fibrosis/27270 "2026-11-02T21:42:46Z")

</div>

Has anyone had an ELF test done? Although this test is ordered to screen for liver fibrosis, it is a measure of systemic inflammation and fibrosis which, as we know, drives all aspect of aging. Unfortunately, it costs \>$ 800 out of pocket, so unaffordable for me. After learning about what ELF measures, I wondered why drugs such as Pirfenidone, montelukast, and others which target fibrotic, infl…

[Previous page](https://www.rapamycin.news/latest.md)

[Next page](https://www.rapamycin.news/latest.md?page=2)
