# News **URL:** https://www.rapamycin.news/c/news/5.md?page=2 [Latest](https://www.rapamycin.news/latest.md) · [Categories](https://www.rapamycin.news/categories.md) · [Tags](https://www.rapamycin.news/tags.md) **Page:** 3 --- ## [Strength and Mobility Work May Pay Off Even in Very Late Life](https://www.rapamycin.news/t/strength-and-mobility-work-may-pay-off-even-in-very-late-life/27309)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [November 1, 2026, 12:11am UTC](https://www.rapamycin.news/t/strength-and-mobility-work-may-pay-off-even-in-very-late-life/27309 "2026-11-01T00:11:29Z")
Researchers at UC Davis, UC Irvine and Kaiser Permanente studied 502 adults aged 90 and older in LifeAfter90, a racially and ethnically diverse cohort of Kaiser Permanente Northern California members. Participants averaged 92.9 years and walked at a usual pace of 0.55 m/s on a 4-meter walk test. Over an average of 3.6 years, 259 died. After adjustment for age, sex, race and ethnicity, and educa… --- ## [Hormones and the Body Clock Shape Each Other Across Life, and Both Lose Their Rhythm With Age](https://www.rapamycin.news/t/hormones-and-the-body-clock-shape-each-other-across-life-and-both-lose-their-rhythm-with-age/27308)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [November 1, 2026, 12:05am UTC](https://www.rapamycin.news/t/hormones-and-the-body-clock-shape-each-other-across-life-and-both-lose-their-rhythm-with-age/27308 "2026-11-01T00:05:21Z")
This narrative review by circadian and neuroendocrine researchers in Germany, the UK, Spain and France describes the two-way relationship between the body’s master clock, the suprachiasmatic nucleus (SCN), and steroid hormones: cortisol-type glucocorticoids, estradiol, progesterone and testosterone. The SCN and tissue clocks set the daily timing of hormone release, and those hormones feed back … --- ## [Regular Tea Drinkers in China Had About 11% Lower Cardiovascular Risk](https://www.rapamycin.news/t/regular-tea-drinkers-in-china-had-about-11-lower-cardiovascular-risk/27307)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 11:48pm UTC](https://www.rapamycin.news/t/regular-tea-drinkers-in-china-had-about-11-lower-cardiovascular-risk/27307 "2026-10-31T23:48:26Z")
Researchers from the Chinese Academy of Medical Sciences, Peking University and collaborators analyzed 485,934 adults from the China Kadoorie Biobank, followed for an average of 9 years. About 31% drank tea at least three days a week. These habitual tea drinkers had an 11% lower hazard of vascular disease overall than non-habitual drinkers, with lower hazards for coronary heart disease, heart a… --- ## [Building Strong Social Ties Before Old Age May Pay Dividends in Functional Capacity](https://www.rapamycin.news/t/building-strong-social-ties-before-old-age-may-pay-dividends-in-functional-capacity/27305)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 10:01pm UTC](https://www.rapamycin.news/t/building-strong-social-ties-before-old-age-may-pay-dividends-in-functional-capacity/27305 "2026-10-31T22:01:15Z")
Researchers led from the Chinese University of Hong Kong pooled data from five large aging cohorts: CHARLS (China), ELSA (England), HRS (USA), SHARE (Europe and Israel) and JSTAR (Japan). In 39,021 adults aged 50 and older, they scored social connection from 0 to 5 using marital status, living with others, family contact, contact with friends or relatives, and social activity participation. The… --- ## [4-Day Diet Trap: How a Brief Fast-Food Binge Permanently Rewires Immune Memory](https://www.rapamycin.news/t/4-day-diet-trap-how-a-brief-fast-food-binge-permanently-rewires-immune-memory/27304)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 7:10pm UTC](https://www.rapamycin.news/t/4-day-diet-trap-how-a-brief-fast-food-binge-permanently-rewires-immune-memory/27304 "2026-10-31T19:10:46Z")
Transient exposure to a high-fat diet for just four days surrounding the onset of inflammation radically and permanently exacerbates disease severity. Using murine models of skin and lung inflammation, researchers demonstrated that this brief dietary window amplifies tissue pathology to levels matching chronic obesity. The damage is mediated by a neutrophil-dependent NLRP3 inflammasome cascade … --- ## [Why Hair Goes Gray, and Why It Occasionally Comes Back](https://www.rapamycin.news/t/why-hair-goes-gray-and-why-it-occasionally-comes-back/27289)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 6\ **Last updated:** [October 31, 2026, 2:20pm UTC](https://www.rapamycin.news/t/why-hair-goes-gray-and-why-it-occasionally-comes-back/27289 "2026-10-31T14:20:57Z")
This review from Taipei Medical University and collaborating Taiwanese institutions brings together what is known about why human hair turns gray. Hair color comes from pigment cells in the hair bulb, which are restocked at the start of every growth cycle from a reserve of melanocyte stem cells higher up in the follicle. The authors describe how these cells develop, the chemistry of the two mai… --- ## [Stay Active and Your Achilles May Handle Eccentric Exercise Like a Young Adult’s](https://www.rapamycin.news/t/stay-active-and-your-achilles-may-handle-eccentric-exercise-like-a-young-adult-s/27298)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 5:03am UTC](https://www.rapamycin.news/t/stay-active-and-your-achilles-may-handle-eccentric-exercise-like-a-young-adult-s/27298 "2026-10-31T05:03:45Z")
Researchers at Nantes University in France compared how the calf muscle and Achilles tendon behave during eccentric exercise, where a muscle produces force while it lengthens, in 14 young adults (average age 22) and 11 physically active older adults (average age 71). Using ultrasound, they tracked the gastrocnemius muscle fibers and the point where muscle meets tendon. Participants exercised on… --- ## [Metabolic Health and Lower Inflammation: Two Levers Against Immune Aging](https://www.rapamycin.news/t/metabolic-health-and-lower-inflammation-two-levers-against-immune-aging/27297)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 4:47am UTC](https://www.rapamycin.news/t/metabolic-health-and-lower-inflammation-two-levers-against-immune-aging/27297 "2026-10-31T04:47:48Z")
This single-author review from China Medical University in Taiwan proposes a model for why aging weakens protective immunity while increasing autoimmunity. The focus is B cells, the immune cells that make antibodies. The author argues that aging first loosens the checkpoints that normally remove or silence self-reactive B cells, both in the bone marrow and in the rest of the body. Changes insid… --- ## [Cutting Back on Sweets and Sugary Drinks May Help Protect the Aging Brain](https://www.rapamycin.news/t/cutting-back-on-sweets-and-sugary-drinks-may-help-protect-the-aging-brain/27296)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 4:36am UTC](https://www.rapamycin.news/t/cutting-back-on-sweets-and-sugary-drinks-may-help-protect-the-aging-brain/27296 "2026-10-31T04:36:43Z")
Using UK Biobank data from about 182,000 adults, researchers in China and Hong Kong grouped people by their food preferences into three profiles: health-aligned, broad-preference and sweet-tooth. The sweet-tooth group, who rated most foods low except sweets and sugary drinks, had a 79% higher hazard of dementia than the health-aligned group over a median of 13.8 years. Their hazard of Alzheimer… --- ## [Exercise May Offset the Aging Cost of Sitting and Poor Sleep, a French Study Hints](https://www.rapamycin.news/t/exercise-may-offset-the-aging-cost-of-sitting-and-poor-sleep-a-french-study-hints/27293)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 31, 2026, 4:17am UTC](https://www.rapamycin.news/t/exercise-may-offset-the-aging-cost-of-sitting-and-poor-sleep-a-french-study-hints/27293 "2026-10-31T04:17:33Z")
Researchers in Toulouse, France, examined how physical activity, sitting time and sleep quality relate, alone and in combination, to five biological aging clocks in 890 adults aged 20 to 102. The clocks were PhenoAge, GrimAge, DunedinPACE, the inflammatory clock iAge, and an intrinsic capacity clock. Activity, sitting and sleep were self-reported by questionnaire. Taken one at a time, the three… --- ## [Fresh Sauerkraut Hints at Lower Inflammation, but More Microbes May Be Needed](https://www.rapamycin.news/t/fresh-sauerkraut-hints-at-lower-inflammation-but-more-microbes-may-be-needed/27290)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [October 31, 2026, 4:04am UTC](https://www.rapamycin.news/t/fresh-sauerkraut-hints-at-lower-inflammation-but-more-microbes-may-be-needed/27290 "2026-10-31T04:04:24Z")
Researchers at the University of Freiburg in Germany asked whether eating sauerkraut every day improves gut barrier function, inflammation, blood sugar control or blood pressure in healthy adults. In a randomized crossover trial, 87 participants ate 100 grams a day of fresh, live-culture sauerkraut for four weeks and pasteurized sauerkraut for another four weeks. Each phase was preceded by a fo… --- ## [Wild Blueberries: The "Elicited" Super-Polyphenol for Vascular Aging?](https://www.rapamycin.news/t/wild-blueberries-the-elicited-super-polyphenol-for-vascular-aging/23503)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 46\ **Last updated:** [October 30, 2026, 7:49pm UTC](https://www.rapamycin.news/t/wild-blueberries-the-elicited-super-polyphenol-for-vascular-aging/23503 "2026-10-30T19:49:47Z")
This comprehensive review argues that wild blueberries (Vaccinium angustifolium) possess a superior cardiometabolic profile compared to their cultivated counterparts, driven by a phenomenon known as “elicitation.” Unlike cultivated highbush berries grown in optimized conditions, wild blueberries survive in harsh northern climates (Maine, Canada) with poor soil and extreme cold. These environmen… --- ## [Bypassing the Ice Bath: The Chemical Switch That Replicates Cold-Induced Longevity](https://www.rapamycin.news/t/bypassing-the-ice-bath-the-chemical-switch-that-replicates-cold-induced-longevity/27284)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 2\ **Last updated:** [October 30, 2026, 6:04pm UTC](https://www.rapamycin.news/t/bypassing-the-ice-bath-the-chemical-switch-that-replicates-cold-induced-longevity/27284 "2026-10-30T18:04:44Z")
A study published in Nature reveals that the life-extending power of cold temperatures is governed by an active, multi-tissue metabolic communication network rather than passive thermodynamic slowing. Exposure to moderate cold triggers body wall muscle in Caenorhabditis elegans to upregulate the rate-limiting enzyme CAT-4, synthesizing dihydrobiopterin (BH2). Instead of acting locally, BH2 trav… --- ## [Protect Your Aging Muscles by Logging Weekly Volume, Not Rest Times](https://www.rapamycin.news/t/protect-your-aging-muscles-by-logging-weekly-volume-not-rest-times/27222)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [October 30, 2026, 2:06pm UTC](https://www.rapamycin.news/t/protect-your-aging-muscles-by-logging-weekly-volume-not-rest-times/27222 "2026-10-30T14:06:56Z")
In a 10-week trial, each volunteer’s legs were trained on a single-leg leg press at 80 percent of maximum. The legs used either 1-minute or 3-minute rests between sets, and the total workload was either matched or left unmatched. Rest length by itself had no measurable effect on muscle growth or strength. Legs that did more total work, whether through longer rests or through extra sets with sho… --- ## [Three Proteins in Your Blood Predict How Fast You're Aging. Here's What You Can Do About It](https://www.rapamycin.news/t/three-proteins-in-your-blood-predict-how-fast-youre-aging-heres-what-you-can-do-about-it/25259)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 25\ **Last updated:** [October 30, 2026, 1:37pm UTC](https://www.rapamycin.news/t/three-proteins-in-your-blood-predict-how-fast-youre-aging-heres-what-you-can-do-about-it/25259 "2026-10-30T13:37:46Z")
Scientists have long suspected that aging, at its molecular core, follows a conserved script — that a mouse dying of old age and a human doing the same are, in some fundamental sense, running the same program. A landmark study published in Nature now provides the most comprehensive evidence yet that this is true, and offers a toolkit to read and score that program in real time from a blood samp… --- ## [Preserving Vitality: Kaempferol Re-establishes Peripheral Immune Defenses Without Thymus Regrowth](https://www.rapamycin.news/t/preserving-vitality-kaempferol-re-establishes-peripheral-immune-defenses-without-thymus-regrowth/27277)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [October 30, 2026, 5:15am UTC](https://www.rapamycin.news/t/preserving-vitality-kaempferol-re-establishes-peripheral-immune-defenses-without-thymus-regrowth/27277 "2026-10-30T05:15:23Z")
A new preclinical study demonstrates that kaempferol, a common dietary flavonoid found in kale, spinach, and berries,effectively mitigates age-associated immune dysfunction and systemic inflammation in mice. Administering kaempferol to nineteen-month-old mice for eight weeks significantly improved physical performance, restoring grip strength and neuromuscular coordination while reducing depres… --- ## [Fortifying the Gut Barrier: How Targeted Micronutrients Counter Inflammaging and Preserve Cellular Youth](https://www.rapamycin.news/t/fortifying-the-gut-barrier-how-targeted-micronutrients-counter-inflammaging-and-preserve-cellular-youth/27276)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 3:59am UTC](https://www.rapamycin.news/t/fortifying-the-gut-barrier-how-targeted-micronutrients-counter-inflammaging-and-preserve-cellular-youth/27276 "2026-10-30T03:59:28Z")
As humans age, chronic low-grade systemic inflammation, termed inflammaging, drives functional decline,immunosenescence, and multimorbidity. This narrative review explores the mechanistic interplay between micronutrient status, gut microbiota dysbiosis, and immune competence. The authors synthesize biological pathways demonstrating that age-related shifts in gut flora increase intestinal permea… --- ## [Gait, Grip, Memory and Mood: Four Measures That Predict How Well You Will Age](https://www.rapamycin.news/t/gait-grip-memory-and-mood-four-measures-that-predict-how-well-you-will-age/27275)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 3:46am UTC](https://www.rapamycin.news/t/gait-grip-memory-and-mood-four-measures-that-predict-how-well-you-will-age/27275 "2026-10-30T03:46:20Z")
Researchers re-analyzed ASPREE, a large randomized trial of daily 100 mg aspirin versus placebo in 18,581 healthy adults aged 65 and older from Australia and the United States. They built an “intrinsic capacity” score from four domains measured each year: cognition, walking speed, grip strength and mood. They then checked the score against frailty, epigenetic clocks and the trial’s main outcome… --- ## [Train Your Visual Search: How Sharpening Spatial Focus Preserves Reading Speed into Your Eighties](https://www.rapamycin.news/t/train-your-visual-search-how-sharpening-spatial-focus-preserves-reading-speed-into-your-eighties/27274)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [October 30, 2026, 3:26am UTC](https://www.rapamycin.news/t/train-your-visual-search-how-sharpening-spatial-focus-preserves-reading-speed-into-your-eighties/27274 "2026-10-30T03:26:19Z")
Italian researchers tested 120 neurologically healthy adults aged 60 to 88 on a large battery of reading, attention, vision and cognitive tasks to find out what drives slower reading with age. Using statistical mediation, they found that general cognitive speed matters most. The Symbol Digit Modalities Test, which combines processing speed, working memory and inhibition, accounted for roughly a… --- ## [Silent Heart Disease Mirrors the Premature Aging of Your Immune System](https://www.rapamycin.news/t/silent-heart-disease-mirrors-the-premature-aging-of-your-immune-system/27273)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 3:03am UTC](https://www.rapamycin.news/t/silent-heart-disease-mirrors-the-premature-aging-of-your-immune-system/27273 "2026-10-30T03:03:04Z")
Coronary artery disease often progresses silently for years before causing symptoms. A cross-sectional clinical study of 967 middle-aged Swedish adults from the SCAPIS cohort investigated whether shifts in adaptive and innate immunity relate to hidden plaque buildup. Using multi-color flow cytometry on fresh whole blood and coronary computed tomography angiography, researchers identified an imm… --- ## [Why Starting Aerobic Training Early Protects Against Middle-Age Muscle Loss](https://www.rapamycin.news/t/why-starting-aerobic-training-early-protects-against-middle-age-muscle-loss/27272)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 2:55am UTC](https://www.rapamycin.news/t/why-starting-aerobic-training-early-protects-against-middle-age-muscle-loss/27272 "2026-10-30T02:55:00Z")
Sarcopenia is typically diagnosed late in life, yet its cellular foundations develop decades before clinical symptoms emerge. This investigation examined gastrocnemius muscle remodeling in male Wistar rats between young adulthood (8 months) and middle age (14 months), corresponding roughly to 22 and 35 human years. The authors evaluated whether lifelong moderate aerobic treadmill running mitiga… --- ## [Eating for Cognitive Reserve: Fresh Foods Slash Odds of Late-Life Dementia](https://www.rapamycin.news/t/eating-for-cognitive-reserve-fresh-foods-slash-odds-of-late-life-dementia/27271)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 2:27am UTC](https://www.rapamycin.news/t/eating-for-cognitive-reserve-fresh-foods-slash-odds-of-late-life-dementia/27271 "2026-10-30T02:27:56Z")
A cross-sectional investigation of 1,017 community-dwelling older adults from the Birjand Longitudinal Aging Study demonstrated that individuals consuming the highest amounts of unprocessed or minimally processed foods experienced a 48 percent reduction in the odds of major neurocognitive disorder compared to the lowest consumers. While contemporary public health messaging frequently identifies… --- ## [Why Empagliflozin’s Cardiovascular Benefit May Start in Your White Blood Cells](https://www.rapamycin.news/t/why-empagliflozin-s-cardiovascular-benefit-may-start-in-your-white-blood-cells/27269)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 1:49am UTC](https://www.rapamycin.news/t/why-empagliflozin-s-cardiovascular-benefit-may-start-in-your-white-blood-cells/27269 "2026-10-30T01:49:30Z")
Sixteen women who were obese and had blood sugar levels on the edge of diabetes took empagliflozin, a common diabetes drug, every day for twelve weeks. Doctors drew their blood three times: before they started, after two weeks, and at the end. They were looking for a particular troublemaker in the blood. Platelets are the tiny cells that help blood clot, and when they get activated they sometim… --- ## [Five Sleep Habits Linked to a 24% Lower Risk of Thyroid Disease](https://www.rapamycin.news/t/five-sleep-habits-linked-to-a-24-lower-risk-of-thyroid-disease/27268)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 12:53am UTC](https://www.rapamycin.news/t/five-sleep-habits-linked-to-a-24-lower-risk-of-thyroid-disease/27268 "2026-10-30T00:53:32Z")
Using data from 499,084 UK Biobank participants aged 37 to 73, researchers at Harbin Medical University built a 0-to-5 healthy sleep score from five self-reported habits: 7 to 8 hours of sleep, morning chronotype, no frequent insomnia, no snoring and no frequent daytime sleepiness. Over roughly 12 years of follow-up, about 15,000 people were diagnosed with thyroid disease. Compared with those s… --- ## [Your 20s Waistline May Shape Your Cancer Risk at 40](https://www.rapamycin.news/t/your-20s-waistline-may-shape-your-cancer-risk-at-40/27266)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 30, 2026, 12:29am UTC](https://www.rapamycin.news/t/your-20s-waistline-may-shape-your-cancer-risk-at-40/27266 "2026-10-30T00:29:51Z")
Using South Korea’s national health insurance database, researchers followed 6,313,338 adults aged 20 to 39 who had a health screening between 2009 and 2012, for an average of 11.2 years. Height, weight and waist were measured, not self-reported. A total of 151,893 cancers were diagnosed. Ten-year cancer incidence rose stepwise from 1.84% at normal weight to 2.24% in class I obesity and 2.62% i… --- ## [Cardio improves how your arteries work, and the fitter and leaner you get, the bigger the gain](https://www.rapamycin.news/t/cardio-improves-how-your-arteries-work-and-the-fitter-and-leaner-you-get-the-bigger-the-gain/27261)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 1\ **Last updated:** [October 29, 2026, 11:40am UTC](https://www.rapamycin.news/t/cardio-improves-how-your-arteries-work-and-the-fitter-and-leaner-you-get-the-bigger-the-gain/27261 "2026-10-29T11:40:22Z")
Researchers from the University of Ljubljana in Slovenia pooled 72 randomized controlled trials, with 3,357 participants, that compared aerobic training against no exercise. They focused on brachial-artery flow-mediated dilation (FMD), an ultrasound test of how well an artery widens in response to increased blood flow. Programs lasting 4 to 26 weeks raised FMD by 2.35 percentage points on avera… --- ## [Toxic By Design: How Water Turns 'Inert' Microplastics Into Spontaneous Free Radical Generators](https://www.rapamycin.news/t/toxic-by-design-how-water-turns-inert-microplastics-into-spontaneous-free-radical-generators/27081)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 8\ **Last updated:** [October 29, 2026, 11:38pm UTC](https://www.rapamycin.news/t/toxic-by-design-how-water-turns-inert-microplastics-into-spontaneous-free-radical-generators/27081 "2026-10-29T23:38:50Z")
Commodity plastics have universally been considered chemically inert. This study reveals a profound paradigm shift: when fragmented into microplastics and suspended in pure water, common materials like polyethylene, polypropylene, and polystyrene spontaneously and continuously generate highly reactive hydroxyl radicals. This physicochemical activity is driven purely by water-hydrophobe interact… --- ## [The $5 Vaccine that Restored Memory and Brain Volume, May Hold a Clue to Dementia Prevention](https://www.rapamycin.news/t/the-5-vaccine-that-restored-memory-and-brain-volume-may-hold-a-clue-to-dementia-prevention/27183)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 4\ **Last updated:** [October 29, 2026, 10:11pm UTC](https://www.rapamycin.news/t/the-5-vaccine-that-restored-memory-and-brain-volume-may-hold-a-clue-to-dementia-prevention/27183 "2026-10-29T22:11:53Z")
Johns Hopkins researchers vaccinated PS19 tauopathy mice with subcutaneous BCG, the live attenuated tuberculosis vaccine, starting at three months of age. Treated animals showed roughly an 80 percent reduction in hippocampal phospho-tau staining, a 75 percent reduction in microglial activation marker Iba1, preserved hippocampal volume and ventricular size on MRI, restored brain glutamate signal… --- ## [Lower Blood Pressure and Blood Sugar Linked to a Younger-Looking Retina and Brain](https://www.rapamycin.news/t/lower-blood-pressure-and-blood-sugar-linked-to-a-younger-looking-retina-and-brain/27259)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 28, 2026, 9:51pm UTC](https://www.rapamycin.news/t/lower-blood-pressure-and-blood-sugar-linked-to-a-younger-looking-retina-and-brain/27259 "2026-10-28T21:51:42Z")
Researchers from the Chinese University of Hong Kong analyzed retinal OCT scans from 28,657 UK Biobank participants aged 40 to 69 and compared them with each person’s Brain Care Score, a 19-point index of modifiable factors including blood pressure, HbA1c, cholesterol, BMI, diet, alcohol, smoking, physical activity, sleep, stress and social relationships. Higher scores were associated with slig… --- ## [Just Lift Something: The New Rules of Strength Training Are Simpler Than You Think](https://www.rapamycin.news/t/just-lift-something-the-new-rules-of-strength-training-are-simpler-than-you-think/27257)
**Author:** [@RapAdmin](https://www.rapamycin.news/u/RapAdmin)\ **Replies:** 0\ **Last updated:** [October 28, 2026, 9:20pm UTC](https://www.rapamycin.news/t/just-lift-something-the-new-rules-of-strength-training-are-simpler-than-you-think/27257 "2026-10-28T21:20:48Z")
The American College of Sports Medicine has replaced its 2009 resistance training guidelines with an evidence-graded umbrella review of 137 systematic reviews covering more than 30,000 adults. Almost every form of resistance training beat doing nothing, improving strength, muscle size, power, endurance, gait speed, balance and functional tests. Only a few programming variables changed results: … [Previous page](https://www.rapamycin.news/c/news/5.md?page=1) [Next page](https://www.rapamycin.news/c/news/5.md?page=3)